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Thread: Faroese genetic homogeneity threatens their existence

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    Default Faroese genetic homogeneity threatens their existence

    Faeroes susceptible to deadly illness

    Monday, 17 May 2010 14:21 RC News

    Islanders suffer from rare genetic illness in far greater numbers than people in the rest of the world

    A deadly genetic disease that is normally very rare is apparently hitting people on the Faroe Islands hard, according to new research.

    The illness is called carnitine transporter deficiency and typically affects only around 1 in 50,000-100,000 people. In Denmark only two Danes have been diagnosed with the disease in the last 30 years.

    But on the Faeroe Islands health authorities have already found nearly 100 people with the condition in just the past few months.

    People with CTD are lacking carnitine, a natural substance used by cells to process fats. Without it the body is unable to convert the fats into energy, and this can cause the heart to pump too hard and suddenly stop.

    Researchers had already been aware of the relatively high incidence of CTD on the Faeroes, but the seriousness of the situation really took hold early last year, when a 21-year-old man died of cardiac arrest at his dorm room. His sister had died a few years earlier, also of a heart attack.

    While the family of the two pressured health authorities for answers, another young woman died of cardiac arrest this past January. This led to health authorities to initiate a free screening programme a few months ago for all 48,000 of the nation’s residents.

    Those who have been diagnosed with the disease will now receive carnitine supplements to correct the illness’ detrimental effects.

    But many Faeroese have been shaken by the breadth of the genetic disease among their population – one which often kills young adults.

    Sissal Kampmann, who lives in Denmark but comes from the Faeroe Islands, has two brothers who were diagnosed with CTD through the screening programme.

    ‘You really panic with this type of illness where you can’t see anything and you have no clue as to whether you’re healthy or not,’ she told public broadcaster DR. ‘And then I began worrying that my daughter might also be ill. It’s been a shock.’

    Health authorities estimate that 1 out of every 500 Faeroese probably carry the gene that causes CTD. It was only 15 years ago that the first cases were discovered, found in two children by a paediatrician.

    Researchers at Rigshospitalet in Copenhagen are now racing to examine as many Faroese as possible for CTD.

    ‘Unfortunately we’ve seen people die from this disease and it can happen very suddenly, so it’s important we find the affected patients and get them treated as soon as possible,’ said Dr. Allan Meldgaard Lund.

    Lund said CTD can jump generations in a family, but to contract the illness both parents must carry the gene.

    Up to 10 percent of the Faroese population appear to be bearers of CTD, according to studies. And many marry other Faeroese, increasing the risk of their children developing the disease.

    But CDT is not the only genetic defect plaguing the Faroese. Researchers say that between 8-10 other serious genetic illnesses are proving to be far more widespread in the Faeroes compared to the rest of the world – including cystic fibrosis, liver diseases and other physical and mental disabilities.

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    ...I assume they will suggest having them all breed with Khoikhoi.



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    Healthy and wonderful.



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    I was thinking I would bring my French-Canadian DNA over there. Faroese men are HOT!

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    Question "Faroese men are HOT!"

    Quote Originally Posted by AcadianDriftwood View Post
    I was thinking I would bring my French-Canadian DNA over there.
    was your plan to become a repository
    of healthy fřroyingar genetic material - exclusively - or
    to include random samples from
    the genetically defective?

    Last edited by lei.talk; 05-19-2010 at 02:39 PM.


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    Are they genetically close to people from the Shetlands ?



    Wake up and smell the coffee.


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    Couldn't they send Icelanders or other Norse peoples there to diversify the gene pool?

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    Quote Originally Posted by Civis Batavi View Post
    Are they genetically close to people from the Shetlands ?
    Yes, they are.

    The Faroes didn't have many people to start with, and then the Black Death hit the place particularly hard, wiping out the population of entire islands in some cases... this probably resulted in a genetic bottleneck of sorts. Then the population tripled after the Second World War.
    Last edited by Grumpy Cat; 02-15-2011 at 04:08 AM.

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    I thought of this happening to them a while back when I was studying genetic disorders amoung isolated gene pools.

    Seems a injection of mainland blood is in order.

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    Quote Originally Posted by AcadianDriftwood View Post
    Yes, they are.

    The Faroes didn't have many people to start with, and then the Black Death hit the place particularly hard, wiping out the population of entire islands in some cases... this probably resulted in a genetic bottleneck of sorts. Then the population tripled after the Second World War.
    Could it be useful to match some Faroese with some people from the Shetlands and the Orkneys ? Then the Faroese blood in general is protected and they get an healthy infusion from a people that is genetically and culturally like them.
    Last edited by The Lawspeaker; 02-15-2011 at 10:46 AM.



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    Quote Originally Posted by Civis Batavi View Post

    Could it be useful to match some Faroese with some people from the Shetlands and the Orkneys ? Then the Faroese blood in general is protected and they get an healthy infusion from a people that is genetically and culturally like them.
    The problem is that Shetland and Orkney islanders also have inherited diseases as a result from inbreeding. Within a few generations the situation would still be the same.

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