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The Sicanians were the original people of all of Sicily, inhabiting the whole island until demographic replacement or assimilation occurred. As they were the first inhabitants, it is likely that they still make up a large portion of Sicilian DNA.
First, the Elymians came from Anatolia, an Indo-European people whose language shared some commonalities with Tyrrhenian (Etruscan, Lemnian, etc), Greek, and Anatolian languages. They settled the northwest corner of the island, pushing the Sicanians westward and assimilating those who remained.
Next, the Sikels, an Italic people from the mainland, settled along the east coast, pushing the Sicanians back westward and assimilating those along the way.
The Sicanians, as such, were pushed toward the center of the island, around Caltanissetta, Agrigento, and part of Palermo.
So who were they?
Iberian? One ancient Greek writer described them as Iberian, but his basis for this was unknown and indeed, there is little genetic similarity today between Sicilians and Iberians to support this, nor is there any frequency worth mentioning of Iberian R1b on the island, much less in the areas that had the highest concentration of Sicanian people.
Afro-Asiatic? Another hypothesis has been that they were Afro-Asiatic speakers, related either to Natufians, Berbers, or both. This could be supported by pyramid-like structures that they built, their contact with ancient Egyptians for trade, and the high prevalence of Near Eastern DNA on the island, especially in regions that have been least touched by Norman, Lombard, Greek, etc. admixture.
Bronze Age natives? Finally, the hypothesis I believe to be the most likely, is that they were the Bronze Age inhabitants, likely of similar stock to the people in the Aegean such as Minoans and Cypriots. This would make sense because of the high frequency of haplogroup G in inland Sicily and Agrigento, which is of Caucasian origin.
Or maybe none of these are right. But my guess is that they were more, not less, Near Eastern than the population is today.
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