PDA

View Full Version : Genotype vs. Phenotype



Sizzo
11-02-2013, 09:21 AM
Any correlation between the 2?

Population
North_Sea 27.62%
Atlantic 18.41%
Baltic 4.83%
Eastern_Euro -
West_Med 22.96%
West_Asian 5.28%
East_Med 20.70%
Red_Sea 0.10%
South_Asian -
Southeast_Asian 0.10%

# Population (source) Distance
1 North_Italian 11.92
2 Tuscan 13.52
3 Spanish_Galicia 13.6
4 Portuguese 13.7
5 Spanish_Extremadura 15.01
6 Spanish_Murcia 15.05
7 Spanish_Cataluna 15.12
8 Spanish_Castilla_Y_Leon 16.01
9 French 16.48
10 Spanish_Andalucia 17.5
11 Spanish_Valencia 17.64
12 Spanish_Castilla_La_Mancha 18.45
13 Spanish_Cantabria 18.67
14 Spanish_Aragon 19.66
15 Greek 20.33
16 Serbian 20.57
17 Romanian 20.68
18 Southwest_French 20.76
19 Bulgarian 21.13
20 Ashkenazi 21.87

(Eurogenes)


http://i39.tinypic.com/24wypeq.jpg

I'm ectomorph (180 x 63)

MfA_
11-02-2013, 12:21 PM
There is usually not.. 23andMe have only 1 million autosomal SNPs out of 3 billions.. and SNPs about our appearance isn't more than 0.0001% of our genome..

Gaston
11-02-2013, 10:48 PM
^ Exactly, you can't infer anything from the ADMIXTURE tests about your looks, except what population you'll likely to look like if you're not recently mixed.

Sizzo
11-10-2013, 10:29 AM
However my paternal haplogroup is Alpo-Celtic, my autosomal DNA is from Bergamo and my appearence is quite Celtic, so I see some coincidence.

Equilibrium
11-10-2013, 03:18 PM
There is usually not.. 23andMe have only 1 million autosomal SNPs out of 3 billions.. and SNPs about our appearance isn't more than 0.0001% of our genome..


While the human genome is made up of about 3 billion base pairs, human genetic variation only accounts for 0.1% to 0.4% of the base pairs. The rest is identical, otherwise we wouldn't all be humans. ;) So there are 10 to 30 million SNPs in humans of which 23andme tests about 1 million selected ones.


Regarding the question of OP: Obviously phenotype correlates with biogeographic ancestry. Somebody with your genome won't turn out looking SSA, or East Asian or South Asian etc.

Jackson
11-10-2013, 03:22 PM
There can be, but only in the regard that if you are genetically likely the population you are part of, that is because of shared ancestry if you are unmixed, and so you should also look like them because of that ancestry - Or at least you should look within the 'range' of what is normal. Although i don't think it goes much deeper than that to be honest. Two people in the same ethnic group can look quite different but be genetically extremely similar, even people in the same family.

Baluarte
11-10-2013, 03:29 PM
Phenotypes work like a mosaic while genotypes work like a chain.

Phenotypical differences always take place, but people from the same or close groups tend to have physical similarities and not vary excessively. Still, overlap takes place naturally and those in the borders of a particular center/population can be confused with atypical members of other center. Mosaic.

Genotypes work like a chain, it doesn't matter how you look like or how you act, it simply traces your origins to relate them to a common source you may have with other individuals or groups of people.

Common genotype cannot determine phenotype because the chosen center is usually arbitrary. Example: There was not a specific and unique momentwere Proto Indo Europeans suddenly morphed into Proto Slavs, yet, genetic research takes Proto Slavs as a solid category to trace "Eastern European" blood. There is no way to know how every member of this prehistoric group looked like, so the best thing you can come up with is an average guess as to how the person MAY look.

That's it.


Humans tend to care about phenotype and culture more than genotype, for the simple reason that they can understand the mosaic of phenotypes much more easily than the chain of genotypes. After all, populations are dynamic.


Just my opinion.

Damiăo de Góis
11-10-2013, 05:38 PM
It usually goes along great together. I'm also a good example of this.

Twistedmind
11-10-2013, 05:41 PM
Any correlation between the 2?

Population
North_Sea 27.62%
Atlantic 18.41%
Baltic 4.83%
Eastern_Euro -
West_Med 22.96%
West_Asian 5.28%
East_Med 20.70%
Red_Sea 0.10%
South_Asian -
Southeast_Asian 0.10%

# Population (source) Distance
1 North_Italian 11.92
2 Tuscan 13.52
3 Spanish_Galicia 13.6
4 Portuguese 13.7
5 Spanish_Extremadura 15.01
6 Spanish_Murcia 15.05
7 Spanish_Cataluna 15.12
8 Spanish_Castilla_Y_Leon 16.01
9 French 16.48
10 Spanish_Andalucia 17.5
11 Spanish_Valencia 17.64
12 Spanish_Castilla_La_Mancha 18.45
13 Spanish_Cantabria 18.67
14 Spanish_Aragon 19.66
15 Greek 20.33
16 Serbian 20.57
17 Romanian 20.68
18 Southwest_French 20.76
19 Bulgarian 21.13
20 Ashkenazi 21.87

(Eurogenes)




I'm ectomorph (180 x 63)
Of course there is. Just people keep forgeting Human appereance is polygenic. There are few factors which determine human appereance:
1) Gennetic material,
2) Climate
3) Nutrition
4) Population bottleneck

If you dont have genes for blue eyes, you would never had them. Also goes for hooked nose etc. But, other factors I mentioned could interfere which genes would triger.