Testosterone levels (genetic marker)

[Gauthier]

Testosterone levels in men

Marker: rs722208


Testosterone is the primary male sex hormone, although it is also present in women. It is responsible for the development of typically masculine sexual features during puberty such as facial and pubic hair, accelerated growth, and a deepening voice. Testosterone has wide-ranging effects on the body and plays roles in muscle maintenance, cognition, and response to challenge. Levels of testosterone naturally decrease with age after puberty. In this study comprising 4,678 Caucasian males, subjects with the GG genotype at rs722208 had 9% lower levels of circulating testosterone on average than subjects with the AA genotype. Men with the AG genotype had about 3% lower testosterone levels.
https://www.23andme.com/you/journal/pre_sex_hormone_regulation/overview/


Average for various populations across the world.

http://img856.imageshack.us/img856/1927/n0l3.jpg (http://img856.imageshack.us/i/n0l3.jpg/)
http://www.snpedia.com/index.php/Rs722208

ASW (African ancestry in Southwest USA);
CEU (Utah residents with Northern and Western European ancestry from the CEPH collection);
CHD (Chinese in Metropolitan Denver, Colorado);
GIH (Gujarati Indians in Houston, Texas);
LWK (Luhya in Webuye, Kenya);
MEX (Mexican ancestry in Los Angeles, California);
MKK (Maasai in Kinyawa, Kenya);
TSI (Tuscans in Italy);
YRI (Yoruba in Ibadan, Nigeria).



If you have a 23andme account you can check your genotype in the following link, at the very bottom of the page:
https://www.23andme.com/you/journal/pre_sex_hormone_regulation/overview/

[Gauthier]

I'm AA: Typical levels of circulating testosterone.

http://img834.imageshack.us/img834/2255/4gmaa.jpg (http://img834.imageshack.us/i/4gmaa.jpg/)

[Linebacker]

I've had problems with overly high testosterone levels since puberty.

Good thing working out helps me with calming the nerves a little.Sex too.

[Black Wolf]

AA here.

[1stLightHorse]

So North/Western Europeans, Tuscans and Mexicans have higher testosterone levels on average than all other groups?

[StonyArabia]

^ It's interesting but really there is not much benefit in it.

[Taiguaitiaoghyrmmumin]

AA http://s29.postimg.org/5q524gsyf/ZZZiuiu.jpg

[Gauthier]

So North/Western Europeans, Tuscans and Mexicans have higher testosterone levels on average than all other groups?

In regard to Mexicans it does coincide with a study I posted some time ago that also included White Americans and Blacks.


Rohrmann S1, Nelson WG, Rifai N, Brown TR, Dobs A, Kanarek N, Yager JD, Platz EA.

CONTEXT: Higher testosterone in black compared with white men has been postulated to explain their higher prostate cancer incidence. Previous studies comparing hormone levels by race might have been limited by size, restricted age variation, or lack of representation of the general population. OBJECTIVE: Our objective was to compare serum testosterone, estradiol, and SHBG concentrations among non-Hispanic black, non-Hispanic white, and Mexican-American men. PARTICIPANTS, DESIGN, AND SETTING: A total of 1413 men aged 20+ yr and who attended the morning examination session of the Third National Health and Nutrition Examination Survey (NHANES III) in 1988-1991 were included in this cross-sectional study. MEASUREMENT: Serum hormone concentrations were measured by electrochemiluminescence immunoassays.

RESULTS: After applying sampling weights and adjusting for age, percent body fat, alcohol, smoking, and activity, testosterone concentrations were not different between non-Hispanic blacks[AFRICAN-AMERICANS] (n = 363; geometric mean, 5.29 ng/ml) and non-Hispanic whites [WHITE AMERICANS](n = 674; 5.11 ng/ml; P > 0.05) but were higher in Mexican-Americans (n = 376; 5.48 ng/ml; P < 0.05).

CONCLUSIONS: Contrary to the postulated racial difference, testosterone concentrations did not differ notably between black and white men. However, blacks had higher estradiol levels. Mexican-Americans had higher testosterone than whites but similar estradiol and SHBG concentrations. Given these findings, it may be equally if not more important to investigate estradiol as testosterone in relation to diseases with racial disparity.

http://www.ncbi.nlm.nih.gov/pubmed/17456570

[Yehiel]

AA

[1stLightHorse]

In regard to Mexicans it does coincide with a study I posted some time ago that also included White Americans and Blacks.

I wonder if it's from Iberians or Natives.

I would guess Iberian. Look at the culture, bullfighting, machismo, going to extremes to prove masculinity.

[Gauthier]

I wonder if it's from Iberians or Natives.

I would guess Iberian. Look at the culture, bullfighting, machismo, going to extremes to prove masculinity.

Seems likely. Check this out.


Dr. Demers and his colleagues have found evidence that testosterone levels and androgen precursor steroids may vary among different ethnic populations.

-- A study of Portuguese, American, and Asian men, for example, revealed that the average testosterone level in the Portuguese subjects was ~ 500, in Americans, ~ 450, and in the Asian population, ~ 400.

-- Larger differences were observed with the androgen precursor steroids like DHEA. Asian men generally have less facial and body hair than Americans, who generally have less than the Portuguese.

http://mentalhealth.about.com/od/mensmentalhealth/l/blmenpause.htm

[Vasconcelos]

-- A study of Portuguese, American, and Asian men, for example, revealed that the average testosterone level in the Portuguese subjects was ~ 500, in Americans, ~ 450, and in the Asian population, ~ 400.

Hulk smash!

:smash::2headsalt::aufsmaul_2::Pruegelknabe::rage: flame

[Black Wolf]

Italians probably rate high levels of the AA genotype as well.

[Äijä]

I wonder if it's from Iberians or Natives.

I would guess Iberian. Look at the culture, bullfighting, machismo, going to extremes to prove masculinity.

It could still be an Eurasian thing, Mexico is if full of Q.

[gold_fenix]

GG

[Damião de Góis]

I'm AG

[RMuller]

I wonder if it's from Iberians or Natives.

I would guess Iberian. Look at the culture, bullfighting, machismo, going to extremes to prove masculinity.

Im not sure about that. Mexico's amerindians were also very tough machos the Aztecs and other Mexican amerindian had a warrior culture. Just look at the other Latino groups they don't have high Testosterone levels like Mexican-Americans and they have Iberian blood to.

Mexicans are great boxers and MMA fighters other latinos not so much.
Moctezuma had 150 women pregnant when the Spaniards arrived.

[Herr Abubu]

AG. FML.

[RMuller]

Men with high Testosterone are more likely to bang women of other races. I believe the Spanish conquistadores that arrived in Mexico with Hernando Cortez had high testosterone.Many Spanish conquistadores had up to 15 cocubines they were also good fighters ,they weren't whimpy lol.

I read Arnold Schwarzenegger Biography. He would bang women of many races he said. He even got his Guatemalean maid pregnant .:rolleyes:



Gov. Schwarzenegger apologizes for saying Latina Politician was "very hot"
http://seattletimes.com/html/politics/2003250475_arnold09.html


Arnold Schwarzenegger Attended Urban Sex Parties
http://diaryofahollywoodstreetking.com/arnold-schwarzenegger-attended-urban-sex-parties/

[Damião de Góis]

None of the iberians who posted so far are AA. Maybe the AAs were more likely to venture in America?

[Altaylardan Tunaya]

AG

[Balmung]

Im not sure about that. Mexico's amerindians were also very tough machos the Aztecs and other Mexican amerindian had a warrior culture. Just look at the other Latino groups they don't have high Testosterone levels like Mexican-Americans and they have Iberian blood to.

Mexicans are great boxers and MMA fighters other latinos not so much.
Moctezuma had 150 women pregnant when the Spaniards arrived.

I'm not sure it translates into being Macho. I think that has more to do with culture than testosterone. I mean look at much of Italy & Iberia. Full of skinny dudes and then compare them to the typical meatheads of Australia. These regions (along with France) were also the regions to birth the whole metrosexual fad. ;) Well I don't think Iberia did. That was mostly Italy & France's fault.

[Oneeye]

AA



http://i1065.photobucket.com/albums/u399/hammer1115/Screenshot2_zps5899f223.png (http://s1065.photobucket.com/user/hammer1115/media/Screenshot2_zps5899f223.png.html)

[Jackson]

Me and my paternal grandfather are AG, but my father and his mother are AA, my mother and aunt are also AG.

[Iloko]

AG

[sonofthedutch]

AA

[Thor2009]

AA here.

[Catkin]

My dad is AA, my mum is GG: I am AG.

[Herr Abubu]

AA



http://i1065.photobucket.com/albums/u399/hammer1115/Screenshot2_zps5899f223.png (http://s1065.photobucket.com/user/hammer1115/media/Screenshot2_zps5899f223.png.html)

Testo master race.

[Ulla]

^ It's interesting but really there is not much benefit in it.

Not so true.

[Ulla]

I'm not sure it translates into being Macho. I think that has more to do with culture than testosterone. I mean look at much of Italy & Iberia. Full of skinny dudes and then compare them to the typical meatheads of Australia. These regions (along with France) were also the regions to birth the whole metrosexual fad. ;) Well I don't think Iberia did. That was mostly Italy & France's fault.

Agree. It doesn't translate into being Macho. Being Macho does not have sex appeal in Italy or France. I mean, not anymore. Italian and French males are still more sophisticated than average Europeans, but generalizations are always bad. You can found lots of perfect metrosexuals also in London, in Amsterdam, in Berlin or New York.

[Äijä]

Agree. It doesn't translate into being Macho. Being Macho does not have sex appeal in Italy or France. I mean, not anymore. Italian and French males are still more sophisticated than average Europeans, but generalizations are always bad. You can found lots of perfect metrosexuals also in London, in Amsterdam, in Berlin or New York.

:crazy:

[Äijä]

I thought Indians were the highest testo people of EuroAsia according to some study made, but they are short so I dont know.

They sure as hell dont look the part.

[Ulla]

:crazy:

I guess, sophisticated and Finns do not get along. :)

[Äijä]

I guess, sophisticated and Finns do not get along. :)

You are right, Finns have better men.

[Mortimer]

Im AA.

[cally]

My father is AA.

[Hithaeglir]

I've had problems with overly high testosterone levels since puberty.

Good thing working out helps me with calming the nerves a little.Sex too.

Neutering might work too :laugh:

[Black Wolf]

I thought Indians were the highest testo people of EuroAsia according to some study made, but they are short so I dont know.

I am short and I am also AA. I am pretty robust still though and have a lot of facial hair. I also have a good amount of body hair

[Volscian]

AA here

[RMuller]

I thought Indians were the highest testo people of EuroAsia according to some study made, but they are short so I dont know.

Who did they test Sikhs,Punjabi's,Dalits,high caste ???

[Iroczor]

I'm AA along with my fam members

http://i61.tinypic.com/2elxego.png

[1stLightHorse]

None of the iberians who posted so far are AA. Maybe the AAs were more likely to venture in America?

Probably same with Australia vs Britain.

[Herr Abubu]

Oh well, you guys might have the genotype, which is uncertain anyway, but I have the phenotype, i.e., certain proof. My digit ratio is the lowest. Low digit ratio master race.

http://www.theapricity.com/forum/showthread.php?132968-What-s-your-digit-ratio&highlight=digit+ratio

[Gauthier]

Oh well, you guys might have the genotype, which is uncertain anyway, but I have the phenotype, i.e., certain proof. My digit ratio is the lowest. Low digit ratio master race.

http://www.theapricity.com/forum/showthread.php?132968-What-s-your-digit-ratio&highlight=digit+ratio

http://img822.imageshack.us/img822/5323/mkrdq.jpg (http://img822.imageshack.us/i/mkrdq.jpg/)

[Herr Abubu]

http://img822.imageshack.us/img822/5323/mkrdq.jpg (http://img822.imageshack.us/i/mkrdq.jpg/)

I've had more than several already, but thank you.

[Black Wolf]

Oh well, you guys might have the genotype, which is uncertain anyway, but I have the phenotype, i.e., certain proof. My digit ratio is the lowest. Low digit ratio master race.

http://www.theapricity.com/forum/showthread.php?132968-What-s-your-digit-ratio&highlight=digit+ratio

My digit ratio must be quite low as well. My ring finger is quite a bit longer than my index finger.

[curupira]

AA.

[Mazik]

AA for both me and my grandpa.

[Kazimiera]

If I was a man: AA

[Gauthier]

Society bloomed with gentler personalities, more feminine faces: Technology boom 50,000 years ago correlated with less testosterone

Date: August 1, 2014

Source: Duke University

Summary: Scientists have shown that human skulls changed in ways that indicate a lowering of testosterone levels at around the same time that culture was blossoming. Heavy brows were out, rounder heads were in. Technological innovation, making art and rapid cultural exchange probably came at the same time that we developed a more cooperative temperament by dialing back aggression with lower testosterone levels.

http://imageshack.com/a/img901/7509/7Gs750.jpg

Modern humans appear in the fossil record about 200,000 years ago, but it was only about 50,000 years ago that making art and advanced tools became widespread.
A new study appearing Aug. 1 in the journal Current Anthropology finds that human skulls changed in ways that indicate a lowering of testosterone levels at around the same time that culture was blossoming.
"The modern human behaviors of technological innovation, making art and rapid cultural exchange probably came at the same time that we developed a more cooperative temperament," said lead author Robert Cieri, a biology graduate student at the University of Utah who began this work as a senior at Duke University.
The study, which is based on measurements of more than 1,400 ancient and modern skulls, makes the argument that human society advanced when people started being nicer to each other, which entails having a little less testosterone in action.
Heavy brows were out, rounder heads were in, and those changes can be traced directly to testosterone levels acting on the skeleton, according to Duke anthropologist Steven Churchill, who supervised Cieri's work on a senior honors thesis that grew to become this 24-page journal article three years later.
What they can't tell from the bones is whether these humans had less testosterone in circulation, or fewer receptors for the hormone.
The research team also included Duke animal cognition researchers Brian Hare and Jingzhi Tan, who say this argument is in line with what has been established in non-human species.
In a classic study of Siberian foxes, animals that were less wary and less aggressive toward humans took on a different, more juvenile appearance and behavior after several generations of selective breeding.
"If we're seeing a process that leads to these changes in other animals, it might help explain who we are and how we got to be this way," said Hare, who also studies differences between our closest ape relatives -- aggressive chimpanzees and mellow, free-loving bonobos.
Those two apes develop differently, Hare said, and they respond to social stress differently. Chimpanzee males experience a strong rise in testosterone during puberty, but bonobos do not. When stressed, the bonobos don't produce more testosterone, as chimps do, but they do produce more cortisol, the stress hormone.
Their social interactions are profoundly different and, relevant to this finding, their faces are different, too. "It's very hard to find a brow-ridge in a bonobo," Hare said.
Cieri compared the brow ridge, facial shape and interior volume of 13 modern human skulls older than 80,000 years, 41 skulls from 10,000 to 38,000 years ago, and a global sample of 1,367 20th century skulls from 30 different ethnic populations.
The trend that emerged was toward a reduction in the brow ridge and a shortening of the upper face, traits which generally reflect a reduction in the action of testosterone.
There are a lot of theories about why, after 150,000 years of existence, humans suddenly leapt forward in technology. Around 50,000 years ago, there is widespread evidence of producing bone and antler tools, heat-treated and flaked flint, projectile weapons, grindstones, fishing and birding equipment and a command of fire. Was this driven by a brain mutation, cooked foods, the advent of language or just population density?
The Duke study argues that living together and cooperating put a premium on agreeableness and lowered aggression and that, in turn, led to changed faces and more cultural exchange.
"If prehistoric people began living closer together and passing down new technologies, they'd have to be tolerant of each other," Cieri said. "The key to our success is the ability to cooperate and get along and learn from one another."

http://www.sciencedaily.com/releases/2014/08/140801171114.htm

[DarknessWin]

I've had problems with overly high testosterone levels since puberty.

Good thing working out helps me with calming the nerves a little.Sex too.

Calm down rambo, come to greece with your sister to take care of you gay

[DarknessWin]

Mediteraneans have the most testosterone, another sudy to prove this. good

[alpha]

I'm AA


I wonder if it's from Iberians or Natives.

I would guess Iberian. Look at the culture, bullfighting, machismo, going to extremes to prove masculinity.


The G allele is much less frequent among Amerindians compared to Europeans and Southern Europeans have a lower G allele frequency compared to other Europeans.

https://alfred.med.yale.edu/alfred/SiteTable1A_working.asp?siteuid=SI003523N

[Linebacker]

Calm down rambo, come to greece with your sister to take care of you gay

You want to teach me in the Ancient Greek art of manlove??



https://s-media-cache-ak0.pinimg.com/236x/aa/0a/9a/aa0a9aa4d72211df61a5ef7a4d2efcbd.jpg

[PunhetaDeBacalhau]

AA here :rage

[de Burgh II]

https://s16.postimg.org/g0cyqcpfp/Untitled.jpg

AG

[firemonkey]

GG

[Newman]

Mediteraneans have the most testosterone, another sudy to prove this. good

Utah whites have the least GG of all the groups..

[Dick]

I've had problems with overly high testosterone levels since puberty.

Good thing working out helps me with calming the nerves a little.Sex too.
BAHAHAHA

[Era]

AA :D

[Bogdan]

AG

[Vasconcelos]

None of the iberians who posted so far are AA. Maybe the AAs were more likely to venture in America?


I'm AA

[barnumandbailey]

Men with high Testosterone are more likely to bang women of other races. I believe the Spanish conquistadores that arrived in Mexico with Hernando Cortez had high testosterone.Many Spanish conquistadores had up to 15 cocubines they were also good fighters ,they weren't whimpy lol.

I read Arnold Schwarzenegger Biography. He would bang women of many races he said. He even got his Guatemalean maid pregnant .:rolleyes:



Gov. Schwarzenegger apologizes for saying Latina Politician was "very hot"
http://seattletimes.com/html/politics/2003250475_arnold09.html


Arnold Schwarzenegger Attended Urban Sex Parties
http://diaryofahollywoodstreetking.com/arnold-schwarzenegger-attended-urban-sex-parties/

This is because a hole is a hole, and sex is sex. High testosterone yields lower inhibition.

[barnumandbailey]

I've had problems with overly high testosterone levels since puberty.

Good thing working out helps me with calming the nerves a little.Sex too.

This is an old comment, but unless you’re suffering from severe medical symptoms of high T levels, your levels aren’t an issue in the slightest.

However, high T is more likely to be considered an issue in civilized societies, as behavioral indicators of high T err towards increased aggression, sex drive, etc. These traits are deemed “unacceptable” and brutish, even though men with higher T levels were more likely to comprise a country or state’s armed forces.

[Linebacker]

This is an old comment, but unless you’re suffering from severe medical symptoms of high T levels, your levels aren’t an issue in the slightest.

However, high T is more likely to be considered an issue in civilized societies, as behavioral indicators of high T err towards increased aggression, sex drive, etc. These traits are deemed “unacceptable” and brutish, even though men with higher T levels were more likely to comprise a country or state’s armed forces.

Yeah that`s from 2014, I was 19 back then, in the absolute peak of my douchebaggery.

Remember I did have problems with unnecessary aggression. But that`s just kinda how Balkan society is for young men.

I say its getting better, kids that are that age today seem more focused on social media and less interested in football hooliganism, drinking and fighting at nightclubs. There still those who do it ofc, but they are far less then they were in my generation.

[Rædwald]

A;G

[Impaler]

AA

[Jana]

Stears gets GG.

[Flashball]

Father: A;G
Mother: A;A
Me: A;A

[Insuperable]

Yeah that`s from 2014, I was 19 back then, in the absolute peak of my douchebaggery.

Remember I did have problems with unnecessary aggression. But that`s just kinda how Balkan society is for young men.

I say its getting better, kids that are that age today seem more focused on social media and less interested in football hooliganism, drinking and fighting at nightclubs. There still those who do it ofc, but they are far less then they were in my generation.

So true. When I was in highschool it was all about hooliganism, fighting and of course girls. Question friends asked each other on saturdays wasn't 'are we going out tonight'. It was 'are we gonna fight tonight'. Up to 10 years after the war in B&H it was all nuts. Nowadays, in a short time it's a whole different world. Everyone is so docile and what you said...social media etc.

[gixajo]

None of the iberians who posted so far are AA. Maybe the AAs were more likely to venture in America?

Me:

rs722208 AG

[hmaohma78]

I got AA

[Defcon2]

GG girly man.

[Brás Garcia de Mascarenhas]

AG

[gixajo]

GG girly man.

But the size of the p *** that is guessed in the photo that you use in your avatar makes up for it.

[Luke35]

A / G

[PT Tagus]

AA

[Zett]

Mom A;A
Dad A;A
Me A;A

[Ruderico]

None of the iberians who posted so far are AA. Maybe the AAs were more likely to venture in America?

I'm AA, my missus is too. We'll kick you in the teeth if you annoy us.

[michal3141]

rs722208 AG

[Hulu]

ESR1 rs722208 152322885 A or G A / A

Of course..

[Benyzero]

Im A/G on this. There is atleast 10 other snps that correlates well with testo and shbg levels. And hundred others on gwas tbh. :) Im thinking about bringing you some good genetic thread again