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View Full Version : MDLP_K23b: aDNA ADMIXTURE RESULTS



Vesuvian Sky
11-17-2014, 04:01 AM
Not sure if a thread like this has been made already, but if not here are various temporal snapshots of autosomal aDNA from various specimens from various locals beginning with the Paleolithic and ending in the Iron Age:


1:

Specimen: Neanderthal
Location/Context: Paleolithic Altai
Date: c. 48,000 BC
http://i58.tinypic.com/2ed5bwg.jpg

2:

Specimen: Ust'-Ishim
Location/Context: Paleolithic Western Siberia
Date: c. 45,000 BC
http://i61.tinypic.com/5am2w6.jpg

3:

Specimen: Kostenki-14
Location/Context: Paleolithic South-West Russia
Date: c. 34,000 BC
http://i61.tinypic.com/8vyycn.jpg

4:

Specimen: Malta Boy
Location/Context: Paleolithic Siberia
Date: c. 24,000 BC
http://i61.tinypic.com/smf3uo.jpg

5:

Specimen: Oleni Ostrov/Karelian Hunter
Location/Context: Mesolithic Russia
Date: c. 5,000 BC
http://i61.tinypic.com/5yvous.jpg

6:

Specimen: Motala
Location/Context: Mesolithic Scandinavia
Date: c. 6,000 BC
http://i58.tinypic.com/1ysids.jpg

7:

Specimen: La Brana
Location/Context: Mesolithic Northern Spain
Date: c. 5,000 BC
http://i62.tinypic.com/2luq3wi.jpg

8:

Specimen: KO1
Location/Context: Neolithic Koros culture of Hungarian Plain
Date: c. 6,000 BC
http://i59.tinypic.com/30tkx7m.jpg

9:

Specimen: LBK
Location/Context: Neolithic Linear Ware culture, Stuttgart, Germany
Date: c. 5,500 BC
http://i60.tinypic.com/1z17eo4.jpg

10:

Specimen: Ajvide58
Location/Context: Late Mesolithic Pitted Ware Culture, Gotland, Sweden
Date: c. 3,000 BC
http://i61.tinypic.com/15rl17m.jpg

11:

Specimen: CO1
Location/Context: Early Copper Age Baden Culture, Hungarian Plain
Date: c. 3,000 BC
http://i57.tinypic.com/j5ci1h.jpg

12:

Specimen: Gokhem_4
Location/Context: Middle Neolithic Funnel Neck Beaker Culture, Scandinavia
Date: c. 3,000 BC
http://i62.tinypic.com/2m2uyh3.jpg

13:

Specimen: Yamnaya
Location/Context: Early Bronze Age Samara Russia
Date: c. 3,000 BC
http://i59.tinypic.com/or02ue.jpg


14:

Specimen: Corded Ware
Location/Context: Late Neolithic Germany
Date: c. 2,600 BC
http://i59.tinypic.com/3022um9.jpg

15:

Specimen: Unetice
Location/Context: Early Bronze Age Germany
Date: c. 2,000 BC
http://i58.tinypic.com/67ku4w.jpg

16:

Specimen: BR
Location/Context: Bronze Age Urn-field culture variant, Hungarian Plain
Date: c. 1,000 BC
http://i62.tinypic.com/28jbihl.jpg

17:

Specimen: IR1
Location/Context: Iron Age Mezocsat culture (Cimmerian), Hungarian Plain
Date: c. 900 BC
http://i62.tinypic.com/98t3rs.jpg

18:

Specimen: Hinxton-2
Location/Context: Iron Age Britain
Date: c. 500 BC to 200 AD
http://i61.tinypic.com/ofswi9.jpg

19:

Specimen: Hinxton-4
Location/Context: Iron Age Britain
Date: c. 500 BC to 200 AD
http://i61.tinypic.com/faqu60.jpg

I'll probably do one for Eurogenes ANE-K7 as well.

Vesuvian Sky
11-17-2014, 12:48 PM
Eurogenes ANE-K7 (http://www.theapricity.com/forum/showthread.php?148047-EG_ANE-K7-aDNA-ADMIXTURE-RESULTS&p=3148446#post3148446) thread is up as well. It seems ANE hides somewhat in WHG. Compared Motala results would appear to suggest this.

Thrax
11-17-2014, 01:58 PM
Again, we notice that during the bronze and iron age (indo-european "invasions") the Hunter Gatherer rises compared to the Neolithic age and South Central Asian also appears. Those components seem to correspond with Eurogene's Baltic, North Atlantic and West Asian, so they could possibly be "Indo-European" markers.

Vesuvian Sky
11-17-2014, 02:14 PM
Again, we notice that during the bronze and iron age (indo-european "invasions") the Hunter Gatherer rises compared to the Neolithic age and South Central Asian also appears. Those components seem to correspond with Eurogene's Baltic, North Atlantic and West Asian, so they could possibly be "Indo-European" markers.

That's more or less what was postulated in Brandt and Haak papers of last year. Though since the Lazaridis paper came out more focus is placed on the terms ANE, WHG, and ENF. ANE is apparently closely connected with IE invasion but from what I've seen it may even be thought of as Indo-Uralic at a rather remote point in time. In this forthcoming paper (http://www.theapricity.com/forum/showthread.php?142743-New-Paper-Corded-Ware-Culture-Population-Turnover-Migration&highlight=corded+ware) concerning genetic change during the CWC horizon, it would seem very much connected with that particular culture.

Insuperable
11-22-2014, 10:29 AM
Eurogenes ANE-K7 (http://www.theapricity.com/forum/showthread.php?148047-EG_ANE-K7-aDNA-ADMIXTURE-RESULTS&p=3148446#post3148446) thread is up as well. It seems ANE hides somewhat in WHG. Compared Motala results would appear to suggest this.

I don't think it is wise to compare results from one calculator with the results from other calculators. Who knows what references they used for say Hunter-Gatherers. If you want to compare Eurogenes K13 with Eurogenes ANE-K7 you would see it tells an another story. There was most likely a diffusion of people with high ANE starting thousands of years ago as claimed which is evident in the following plot.
http://i62.tinypic.com/2d5or7.jpg

The purest Hunter-Gatherers would be those like La Brana (western hunter-gatherers) who do have the lowest ANE score on ANE-K7 compared to others.

Longbowman
11-22-2014, 10:53 AM
Fascinating :)

Vesuvian Sky
11-22-2014, 11:14 AM
I don't it is wise to compare results from one calculator with the results from other calculators. Who knows what references they used for say Hunter-Gatherers. If you want to compare Eurogenes K13 with Eurogenes ANE-K7 you would see it tells an another story. There was most likely a diffusion of people with high ANE starting thousands of years ago as claimed which is evident in the following plot.
http://i62.tinypic.com/2d5or7.jpg
The purest Hunter-Gatherers would be those like La Brana (western hunter-gatherers) who do have the lowest ANE score on ANE-K7 compared to others.

Well La Brana has both an east Eurasian and ANE component per EG_ANE-K7. He's relatively purer according to that calc., but really all these calculators use what's known as 'fuzzy logic (http://en.wikipedia.org/wiki/Fuzzy_logic)' implying a certain degree of subjectivity is used to take place based on what reference populations are used and what not. So what I'm getting at is who knows for sure what component is more true than others per calc. and what's really buried in them.

Insuperable
11-22-2014, 02:49 PM
Well La Brana has both an east Eurasian and ANE component per EG_ANE-K7. He's relatively purer according to that calc., but really all these calculators use what's known as 'fuzzy logic (http://en.wikipedia.org/wiki/Fuzzy_logic)' implying a certain degree of subjectivity is used to take place based on what reference populations are used and what not. So what I'm getting at is who knows for sure what component is more true than others per calc. and what's really buried in them.

Of course we can't know which component is more true just by looking at calculator results. I can use solely Motala as a reference for Hunter-Gatherers and Hunter-Gatherers closer to Motala would turn out to be purer if you get my point. But it is written in articles how there was a third player in the game beside HG and Farmers. ("http://www.theguardian.com/science/2014/sep/18/ancient-ancestors-europeans-dna-study) I think they starting entering Europe a bit earlier than 5000 years ago. Having that and PCA plots on mind we can draw some conclusions who are still bogus for now nevertheless. Some HGs had both minor admixtures. Anyway, it is not really important what tools are used. Btw admixture is calculated using Bayesian clustering algorithm based on Markov models or expectation-maximization algorithms. Eurogenes, Dodecad and similar use ADMIXTURE or STRUCTURE software which are based on similar things.

I could still be wrong so don't take me seriously.

Vesuvian Sky
11-22-2014, 03:04 PM
Of course we can't know which component is more true just by looking at calculator results. I can use solely Motala as a reference for Hunter-Gatherers and Hunter-Gatherers closer to Motala would turn out to be purer if you get my point. But it is written in articles how there was a third player in the game beside HG and Farmers. ("http://www.theguardian.com/science/2014/sep/18/ancient-ancestors-europeans-dna-study) I think they starting entering Europe a bit earlier than 5000 years ago. Having that and PCA plots on mind we can draw some conclusions who are still bogus for now nevertheless. Some HGs had both minor admixtures. Anyway, it is not really important what tools are used. Btw admixture is calculated using Bayesian clustering algorithm based on Markov models or expectation-maximization algorithms. Eurogenes, Dodecad and similar use ADMIXTURE or STRUCTURE software which are based on similar things.

I could still be wrong so don't take me seriously.

Link didn't work for me but I assume it was about Laziridis et al. paper?

I think I see what you're getting at but just to be clear: I'm not denying the existence of an ANE component.

My concerns are over how things are measured more appropriately and what the exact temporal rate of occurrence is. Essentially accuracy vs. precision.

Rather I'm expecting ANE increase within last 5000 years because of this forthcoming paper:

http://www.theapricity.com/forum/showthread.php?142743-New-Paper-Corded-Ware-Culture-Population-Turnover-Migration&highlight=corded+ware

Vesuvian Sky
12-02-2014, 10:01 PM
I added the Iron Age IR1 (now number 13) results from the Gamba study because its apparently an ancient Cimmerian specimen. Very fascinating indeed as half the DNA is like what you'd expect an ancient/archaic steppic C. Asian to be before the Neolithic but the other half like a Neolithic farmer: West Asian and Med. Most of the nomadic Iranic tribes like the Cimmerians were theorized to have originated on the C. Asian steppes but the Cimmerians are said by Herodotus to have spent some time just north of the Caucasus. They are of course associated with the Srubna culture before being forced off the Pontic Steppes by the Scythians:

http://books.google.com/books?id=tzU3RIV2BWIC&pg=PA541&lpg=PA541&dq=srubna+culture&source=bl&ots=wWk30553aJ&sig=auE1EI969KEFwWyhOmX0FBrCXJY&hl=en&sa=X&ei=RUR-VMHfEJS2yATJs4CIBw&ved=0CDcQ6AEwBg#v=onepage&q=srubna%20culture&f=false

IR1's DNA reflects all this well. I'll also add these results to EG_ANE-7 thread.

Vesuvian Sky
03-10-2015, 04:33 AM
UPDATE:

M652848 - Oleniy Ostrov
M020637 Yamna
M966366 Corded
M370010 Unetice

All added.

Special thanks to Not a Cop for providing kit number. You da' man.:thumb001:

Forthcoming update for the EG_ANE-7 thread pending.