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View Full Version : Exploring Cuba’s population structure and demographic history using genome-wide data



Brás Garcia de Mascarenhas
07-31-2018, 09:14 AM
"Abstract


Cuba is the most populated country in the Caribbean and has a rich and heterogeneous genetic heritage. Here, we take advantage of dense genomic data from 860 Cuban individuals to reconstruct the genetic structure and ancestral origins of this population. We found distinct admixture patterns between and within the Cuban provinces. Eastern provinces have higher African and Native American ancestry contributions (average 26% and 10%, respectively) than the rest of the Cuban provinces (average 17% and 5%, respectively). Furthermore, in the Eastern Cuban region, we identified more intense sex-specific admixture patterns, strongly biased towards European male and African/Native American female ancestries. Our subcontinental ancestry analyses in Cuba highlight the Iberian population as the best proxy European source population, South American and Mesoamerican populations as the closest Native American ancestral component, and populations from West Central and Central Africa as the best proxy sources of the African ancestral component. Finally, we found complex admixture processes involving two migration pulses from both Native American and African sources. Most of the inferred Native American admixture events happened early during the Cuban colonial period, whereas the African admixture took place during the slave trade and more recently as a probable result of large-scale migrations from Haiti."

Source: https://www.nature.com/articles/s41598-018-29851-3

Morena
07-31-2018, 04:55 PM
This confirms other studies on the subject.

Carlito's Way
08-01-2018, 03:48 AM
This confirms other studies on the subject.

that study is using an old study from 2014 as a reference sample
that 2014 study isnt accurate at all

when they finally test cubans from different regions using better methods then we will finally know more about cuba

Morena
08-01-2018, 03:22 PM
that study is using an old study from 2014 as a reference sample
that 2014 study isnt accurate at all

when they finally test cubans from different regions using better methods then we will finally know more about cuba

How so? It matched up what we already know, that NW Cuba is more European and most NA remained in the SE, for example.

Carlito's Way
08-01-2018, 06:46 PM
How so? It matched up what we already know, that NW Cuba is more European and most NA remained in the SE, for example.

nope. until they have a new study with a better method we will know better

Morena
08-02-2018, 02:27 PM
nope. until they have a new study with a better method we will know better

How was it wrong? you didn't answer my question. It matched up with what we already know about the history of Cuba.

I'm familiar with the work through Razib Khan. He didn't bring up any faults in the methodology used other than a small sample size. Perhaps a larger sample size would change things a little, but I doubt it, given that there is nothing mysterious about the history of Cuba.

Selurong
08-02-2018, 02:35 PM
Cuba needs more attention and larger sample sizes.