Pallantides
04-26-2011, 04:38 PM
http://www.biomedcentral.com/content/pdf/1471-2148-10-304.pdf
Abstract
Background: Tracing the genetic origin of central European farmer N1a lineages can provide a unique opportunity
to assess the patterns of the farming technology spread into central Europe in the human prehistory. Here, we
have chosen twelve N1a samples from modern populations which are most similar with the farmer N1a types and
performed the complete mitochondrial DNA genome sequencing analysis. To assess the genetic and
phylogeographic relationship, we performed a detailed survey of modern published N1a types from Eurasian and
African populations.
Results: The geographic origin and expansion of farmer lineages related N1a subclades have been deduced from
combined analysis of 19 complete sequences with 166 N1a haplotypes. The phylogeographic analysis revealed that
the central European farmer lineages have originated from different sources: from eastern Europe, local central
Europe, and from the Near East via southern Europe.
Conclusions: The results obtained emphasize that the arrival of central European farmer lineages did not occur via
a single demic diffusion event from the Near East at the onset of the Neolithic spread of agriculture into Europe.
Indeed these results indicate that the Neolithic transition process was more complex in central Europe and
possibly the farmer N1a lineages were a result of a ‘leapfrog’ colonization process.
Abstract
Background: Tracing the genetic origin of central European farmer N1a lineages can provide a unique opportunity
to assess the patterns of the farming technology spread into central Europe in the human prehistory. Here, we
have chosen twelve N1a samples from modern populations which are most similar with the farmer N1a types and
performed the complete mitochondrial DNA genome sequencing analysis. To assess the genetic and
phylogeographic relationship, we performed a detailed survey of modern published N1a types from Eurasian and
African populations.
Results: The geographic origin and expansion of farmer lineages related N1a subclades have been deduced from
combined analysis of 19 complete sequences with 166 N1a haplotypes. The phylogeographic analysis revealed that
the central European farmer lineages have originated from different sources: from eastern Europe, local central
Europe, and from the Near East via southern Europe.
Conclusions: The results obtained emphasize that the arrival of central European farmer lineages did not occur via
a single demic diffusion event from the Near East at the onset of the Neolithic spread of agriculture into Europe.
Indeed these results indicate that the Neolithic transition process was more complex in central Europe and
possibly the farmer N1a lineages were a result of a ‘leapfrog’ colonization process.