Nebula

[Slavic Italian]

They look legit. I am considering giving this a shot.

https://www.nebula.org/

[pulstar]

They look legit. I am considering giving this a shot.

https://www.nebula.org/

Sweet find Slavic Italian. Their data security seems better than those of other companies offering similar service at first sight, but also they offer you health risks based on your genome (something I find interesting and something I would pay for) other than more or less simple ancestry test (something I don't find interesting at all).

[Lemgrant]

https://wesbite-nebula.s3.amazonaws.com/css/img/brochure-graphic-1.jpg

we provide more accurate and comprehensive analysis: Our next-generation sequencing technology can read out whole genomes, while most of our competitors use outdated technologies that would capture only a tiny percentage of your genetic information.


The accuracy of your results will depend on whether you choose low-pass or clinical-grade Whole Genome Sequencing. Low-pass sequencing reads out your genome at a lower depth than clinical-grade sequencing (0.4x vs. 30x average coverage). The results obtained from low-pass sequencing data have an accuracy of ~99%, while clinical-grade sequencing produces results that are >99.99% accurate. Low-pass sequencing is much more affordable than clinical-grade sequencing, yet it generates thousands of times more data than the outdated technologies our competitors offer at similar prices.


nice

[Ayetooey]

From the buy now page.

"We currently only support shipments in the United States, please stay tuned for international support".

[Dick]

whole genome sequencing for 99 bucks? wtf

[Slavic Italian]

I ordered it.

[karakartal]

Co-founded by Harvard DNA sequencing pioneer George Church, his graduate student Dennis Grishin and entrepreneur and former Google employee Kamal Obbad.

[Lemgrant]

I ordered it.

I'm curious to see how their ancestry report looks like

[Slavic Italian]

I'm curious to see how their ancestry report looks like

Me too.

[karakartal]

6 months later they will take order in Europe region.

[Slavic Italian]

I'm curious to see how their ancestry report looks like

I just traded emails with them and at this stage they do not know how they are going to set up their reports. They did say as simple as possible for the common customer.

[Slavic Italian]

I sent out my sample today. Looking forward to the results.

[Ayetooey]

I sent out my sample today. Looking forward to the results.

Considering how mixed you are it'll be interesting to see if they break your components up accurately. I look forward to your results.

[Slavic Italian]

Considering how mixed you are it'll be interesting to see if they break your components up accurately. I look forward to your results.

Yeah I am pretty anxious to see how they do.

[Ayetooey]

Yeah I am pretty anxious to see how they do.

Do you know how many reference populations they have? I can't find any information about it.

[Slavic Italian]

Do you know how many reference populations they have? I can't find any information about it.

I have found next to no info. I contacted the staff and they are still trying to determine how they are going to set up the reports.

[Lucas]

Ethnicity report is not so important I think. Biggest deal is full genome sequence for low price. You can estimate deepest subclades for YDNA and mtDNA for example (using other tools).
I consider about buying it too.

[Dick]

I already have credits for a free kit via their website. Just need to wait until they start shipping internationally.

[Ford]

Is there any catch or something? 99 dollars for full genome sounds weird as hell. I'll probably do it when/if they start shipping to Europe.

[Dick]

Is there any catch or something? 99 dollars for full genome sounds weird as hell. I'll probably do it when/if they start shipping to Europe.

For now it's a Low-pass Whole Genome Sequencing (0.4x coverage) but in the future it will be 30x coverage

[Dick]

here is a screenshot of an example from their website. She's supposed to be 50% Aboriginal? :confused:


https://i.imgur.com/Gg8Dvtf.png

[Slavic Italian]

here is a screenshot of an example from their website. She's supposed to be 50% Aboriginal? :confused:


https://i.imgur.com/Gg8Dvtf.png

I should have my results in about five weeks.

[Dick]

I should have my results in about five weeks.

Nice. I assume the raw data should work on Gedmatch genesis

[Slavic Italian]

Nice. I assume the raw data should work on Gedmatch genesis

We'll find out.

[Dick]

We'll find out.

their website says it's a VCF file but you can convert it to a normal file(23andme, ftdna etc) with Dnakitstudio if it dosn't work.

[Slavic Italian]

their website says it's a VCF file but you can convert it to a normal file(23andme, ftdna etc) with Dnakitstudio if it dosn't work.

I'll just send it to LukasM

[Dick]

I'll just send it to LukasM

Good idea xD

[Slavic Italian]

I just received my results. They are accurate it seems. They reinforce the accuracy of K36 report to be honest. The info is very general. They nailed my muscle mass and high testosterone levels in the traits feature. They nailed all my habits and so forth. They need to add sub categories, imo.

72% North/Central European:German, British, and Irish being the references
25% Med:Malta, Sicily, Cyprus, Albania, and Bulgaria.
3% Central Asia: Hazara, Uygur, Uzbek, and Kalash.

[Lemgrant]

I just received my results. They are accurate it seems. They reinforce the accuracy of K36 report to be honest. The info is very general. They nailed my muscle mass and high testosterone levels in the traits feature. They nailed all my habits and so forth. They need to add sub categories, imo.

72% North/Central European:German, British, and Irish being the references
25% Med:Malta, Sicily, Cyprus, Albania, and Bulgaria.
3% Central Asia: Hazara, Uygur, Uzbek, and Kalash.

and where is your Slavic and Finnish input?
https://www.theapricity.com/forum/showthread.php?272017-My-average-IBD-cM-per-population-per-Davidski

[Slavic Italian]

and where is your Slavic and Finnish input?
https://www.theapricity.com/forum/showthread.php?272017-My-average-IBD-cM-per-population-per-Davidski

Yeah. I thought the results were quite vague. Every other test has detected those ethnicities. Nebula told me they are not done with things yet.

[Dick]

Yeah. I thought the results were quite vague. Every other test has detected those ethnicities. Nebula told me they are not done with things yet.

Can you upload the raw data to gedmatch

[Slavic Italian]

Can you upload the raw data to gedmatch

Lukas is working on that for me.

[MagnusDark]

Is this the same service claiming to allow you control of third party use as well as receiving compensation for participating in research? I forget where but I read about one article discouraging it for privacy reasons. The ancestry results seem all too generic. And combining loosely related populations into one cluster is also problematic. Hopefully it improves. I may hold off until then.

[Slavic Italian]

Is this the same service claiming to allow you control of third party use as well as receiving compensation for participating in research? I forget where but I read about one article discouraging it for privacy reasons. The ancestry results seem all too generic. And combining loosely related populations into one cluster is also problematic. Hopefully it improves. I may hold off until then.

They are going to make adjustments. Funny thing is on gedmatch it is deadly accurate.

[MagnusDark]

They are going to make adjustments. Funny thing is on gedmatch it is deadly accurate.

Yea. I imagine it all comes down to algorithms. In truth I really doesn’t matter what they label the components. They could just use the average for each ethnic group to break it down regionally.

Now this is basically claiming to be a full genome autosomal test?

Was the gedmatch result shocking compared to 23andme that is just a fragment of our genetic code? Or was it roughly the same but more accurate with closer distances? It may be useful just for the DNA file.

[Slavic Italian]

Yea. I imagine it all comes down to algorithms. In truth I really doesn’t matter what they label the components. They could just use the average for each ethnic group to break it down regionally.

Now this is basically claiming to be a full genome autosomal test?

Was the gedmatch result shocking compared to 23andme that is just a fragment of our genetic code? Or was it roughly the same but more accurate with closer distances? It may be useful just for the DNA file.

This. It also got a little more closer as far as specifics. It's roughly the same but more accurate with closer distances. The raw data file is huge. Much larger than the other DNA services so this makes it worth it alone. To be honest. When you compare to the Gedmatch results the DNA Tribes SNP Analysis was very comparable which makes me wonder now. Too bad they closed shop four months ago.

[Lemgrant]

This. It also got a little more closer as far as specifics. It's roughly the same but more accurate with closer distances. The raw data file is huge. Much larger than the other DNA services so this makes it worth it alone. To be honest. When you compare to the Gedmatch results the DNA Tribes SNP Analysis was very comparable which makes me wonder now. Too bad they closed shop four months ago.
How many SNPs are used in Eurogenes K13 calculator ? Post your results

[Slavic Italian]

181319 SNPs used in this evaluation prior to oracles.

Admix Results (sorted):


# Population Percent
1 North_Atlantic 34.87
2 Baltic 24.79
3 West_Med 13.98
4 East_Med 11.56
5 West_Asian 7.66
6 South_Asian 3.94
7 Amerindian 1.99


Finished reading population data. 204 populations found.
13 components mode.

--------------------------------

Least-squares method.

Using 1 population approximation:
1 Austrian @ 7.613097
2 Hungarian @ 8.402154
3 West_German @ 9.795560
4 East_German @ 9.961194
5 Serbian @ 10.564109
6 South_Dutch @ 11.753267
7 French @ 12.996634
8 Romanian @ 13.869241
9 Croatian @ 14.251651
10 Moldavian @ 14.300893
11 North_German @ 15.310358
12 Bulgarian @ 17.283081
13 Southeast_English @ 17.593597
14 Danish @ 17.906704
15 North_Dutch @ 18.467068
16 South_Polish @ 19.145548
17 Swedish @ 19.289001
18 Orcadian @ 19.320198
19 Portuguese @ 19.489849
20 Spanish_Cataluna @ 19.538673

Using 2 populations approximation:
1 50% Bulgarian +50% Danish @ 3.822321


Using 3 populations approximation:
1 50% Danish +25% Greek_Thessaly +25% Moldavian @ 3.474034


Using 4 populations approximation:
++++++++++++++++++++++++++++++++++++++++++++++++++ +++++++++++++++++++++++++++++++++++++++++++
1 Danish + Danish + Greek_Thessaly + Moldavian @ 3.474034
2 Greek_Thessaly + Moldavian + North_German + Southeast_English @ 3.475488
3 Danish + Greek_Thessaly + Moldavian + Southeast_English @ 3.485149
4 Croatian + Danish + Greek_Thessaly + West_German @ 3.501608
5 Danish + Greek_Thessaly + Moldavian + North_German @ 3.537469
6 Danish + Greek_Thessaly + Moldavian + West_German @ 3.630763
7 North_German + South_Italian + Southeast_English + Ukrainian @ 3.633320
8 Greek_Thessaly + Hungarian + North_German + West_German @ 3.635470
9 Danish + Danish + South_Italian + Ukrainian @ 3.638009
10 Danish + Danish + South_Italian + Ukrainian_Lviv @ 3.648575
11 Croatian + Danish + Greek_Thessaly + South_Dutch @ 3.649541
12 Danish + South_Italian + Southeast_English + Southwest_Russian @ 3.651827
13 Danish + Greek_Thessaly + Romanian + Swedish @ 3.654924
14 Danish + North_German + South_Italian + Ukrainian @ 3.655092
15 Danish + Polish + South_Italian + West_German @ 3.661082
16 Greek_Thessaly + Moldavian + North_German + Orcadian @ 3.664174
17 Danish + Greek_Thessaly + Hungarian + West_German @ 3.668244
18 Danish + South_Italian + Southeast_English + Ukrainian @ 3.697066
19 Danish + Greek_Thessaly + Moldavian + South_Dutch @ 3.702691
20 Kargopol_Russian + South_Italian + Southeast_English + Southeast_English @ 3.704996

[Slavic Italian]

Eurogenes EUtest V2 K15 4-Ancestors Oracle
This program is based on 4-Ancestors Oracle Version 0.96 by Alexandr Burnashev.
Questions about results should be sent to him at: Alexandr.Burnashev@gmail.com
Original concept proposed by Sergey Kozlov.
Many thanks to Alexandr for helping us get this web version developed.

Admix Results (sorted):


# Population Percent
1 North_Sea 22.35
2 Atlantic 22.17
3 Baltic 14.72
4 West_Med 10.34
5 Eastern_Euro 9.93
6 East_Med 8.36
7 West_Asian 6.39
8 South_Asian 3.50
9 Amerindian 1.64


Finished reading population data. 207 populations found.
15 components mode.

--------------------------------

Least-squares method.

Using 1 population approximation:
1 Austrian @ 6.559654
2 Hungarian @ 8.710988
3 Serbian @ 9.163255
4 East_German @ 9.238798
5 South_Dutch @ 11.392007
6 Croatian @ 12.006701
7 French @ 12.447771
8 Romanian @ 12.725104
9 West_German @ 13.210207
10 Moldavian @ 13.238665
11 North_German @ 14.419765
12 Bulgarian @ 15.911630
13 Spanish_Cataluna @ 16.952246
14 Spanish_Galicia @ 17.020323
15 South_Polish @ 17.357046
16 Southwest_English @ 17.416019
17 Southwest_Finnish @ 17.537947
18 Portuguese @ 17.681952
19 Southeast_English @ 17.739645
20 Ukrainian_Lviv @ 17.897337

Using 2 populations approximation:
1 50% Bulgarian +50% North_German @ 4.361810


Using 3 populations approximation:
1 50% Austrian +25% Greek_Thessaly +25% Irish @ 3.711815


Using 4 populations approximation:
++++++++++++++++++++++++++++++++++++++++++++++++++ ++++++++++++++++++++++++++++++++++++++++++
1 Austrian + Austrian + Greek_Thessaly + Irish @ 3.711815
2 Austrian + East_German + Greek + Irish @ 3.753122
3 Austrian + Austrian + Greek_Thessaly + West_Scottish @ 3.760711
4 Austrian + Danish + East_German + Greek @ 3.768601
5 French + Greek + Irish + Russian_Smolensk @ 3.775407
6 French + Greek + Russian_Smolensk + Southeast_English @ 3.791226
7 Danish + French + Greek + Russian_Smolensk @ 3.804894
8 Austrian + Austrian + Greek + Orcadian @ 3.809607
9 Austrian + East_German + Greek + Southeast_English @ 3.811239
10 French + Greek + Orcadian + Russian_Smolensk @ 3.812169
11 Croatian + Greek + North_German + North_German @ 3.812529
12 French + Greek + Irish + Southwest_Russian @ 3.824938
13 French + Greek + Russian_Smolensk + West_Scottish @ 3.826373
14 Austrian + Austrian + Greek_Thessaly + Southeast_English @ 3.827401
15 Croatian + Greek + North_German + Southeast_English @ 3.829611
16 Austrian + Austrian + Danish + Greek_Thessaly @ 3.831846
17 Greek + Russian_Smolensk + South_Dutch + Southeast_English @ 3.832620
18 Austrian + East_German + Greek + West_Scottish @ 3.833174
19 Croatian + Greek + North_German + South_Dutch @ 3.835448
20 French + Greek + Irish + Ukrainian_Belgorod @ 3.844901

[Lemgrant]

It looks worse than your previous results. I don’t see Italian so much in your oracles and distances are bigger in 4 populations approximation.
https://www.theapricity.com/forum/showthread.php?263456-My-Gedmatch-K13-results

[MagnusDark]

This. It also got a little more closer as far as specifics. It's roughly the same but more accurate with closer distances. The raw data file is huge. Much larger than the other DNA services so this makes it worth it alone. To be honest. When you compare to the Gedmatch results the DNA Tribes SNP Analysis was very comparable which makes me wonder now. Too bad they closed shop four months ago.

I may get it for the file alone. Could I message you how to convert it? I don’t know all that stuff lol.

I miss DNA tribes. I’m mad I didn’t get to use it for my mom or dad before they shut it down. Why did they any ways?

I know YDNA and Autosomal is separate but I thought some old admixtures would show up. Aside from some minimal percent for Tunisian Jew/ Persian Jew and Sephardic Jew(which I have never gotten in other tests) it was mostly very accurate. Only confusion was I got some Denmark and no East European despite my YDNA. And I thought it was ancient alleles?

That’s why I want to do the full genome autosomal test. It should paint the most accurate picture. All my dna kits jump around a bit. My living dna is further north. My ancestry dna is further south with 23 just a smidge north of my ancestrydna on most pcas.

[Slavic Italian]

I may get it for the file alone. Could I message you how to convert it? I don’t know all that stuff lol.

I miss DNA tribes. I’m mad I didn’t get to use it for my mom or dad before they shut it down. Why did they any ways?

I know YDNA and Autosomal is separate but I thought some old admixtures would show up. Aside from some minimal percent for Tunisian Jew/ Persian Jew and Sephardic Jew(which I have never gotten in other tests) it was mostly very accurate. Only confusion was I got some Denmark and no East European despite my YDNA. And I thought it was ancient alleles?

That’s why I want to do the full genome autosomal test. It should paint the most accurate picture. All my dna kits jump around a bit. My living dna is further north. My ancestry dna is further south with 23 just a smidge north of my ancestrydna on most pcas.

None of them are going to be perfect. I did not convert these files. I had Lukas do it for me.

[Slavic Italian]

It looks worse than your previous results. I don’t see Italian so much in your oracles and distances are bigger in 4 populations approximation.
https://www.theapricity.com/forum/showthread.php?263456-My-Gedmatch-K13-results

This is the email response I received.

Hey *&^%,

With regard to Ancestry, granularity depends on the number of people who use our service.
The ancestry reports will become more detailed over time as our user base grows. I'm going
to forward your question about your Y Chromosome to our co-founder and chief scientist,
Dennis Grishin, who can provide more insight into this–my apologies for any delays, busy
time around Nebula HQ : )

Thanks again for all of your support and patience!
Ken