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View Full Version : Do you have this Steppe allele?



Sika
04-03-2019, 02:19 AM
Looks like it was introduced by steppe Yamnaya/ANE people to Europe.

Those with TT (A alleles in yellow on map) will have dry earwax and no body odour.
http://blogs.discovermagazine.com/gnxp/files/2010/10/abcc11A.png

In Europe, it peaks in Eastern Europeans at 20% but it's likely higher than that in Russians looking at the map.

Iberia - 7%

Germany - 16%

Western European - 17 %

Eastern European - 20 %

Japanese - 76%

Korean - 100%



https://upload.wikimedia.org/wikipedia/commons/3/31/World_map_ABCC11_A_Allele.svg
World map of the distribution of the A allele of the single nucleotide polymorphism rs17822931 in the ABCC11 gene. The proportion of A alleles in each population is represented by the white area in each circle.


You can also check this in your 23andme under earwax, are you CC, CT or TT?


http://www.snpedia.com/index.php/Rs17822931
rs17822931
http://i67.tinypic.com/accpr5.jpg

Nazarene
04-03-2019, 02:21 AM
I have literally every steppe allele, i am full blooded yamnaya mashallah

Rgvgjhvv
04-03-2019, 02:36 AM
I don't know

Nazarene
04-03-2019, 02:38 AM
I don't know

Greeks are actually Middle Eastern

Rgvgjhvv
04-03-2019, 02:42 AM
Greeks are actually Middle Eastern

True

Luke35
04-03-2019, 03:01 AM
Nope, I'm CC. But I definitely have less body odor than average. There must be other factors at play in bo determination than just this allele.

Thambi
04-03-2019, 03:11 AM
I'm CT. slightly better body odor. In the subcontinent atleast, its not steppe derived. The no bodyodor genotype (TT) is actually found at a higher frequency among lower castes due to their proximity to eastern eurasians.

here's mine
https://i.imgur.com/GeMzMp8.png

Sika
04-05-2019, 12:48 AM
There must be other factors at play in bo determination than just this allele.

It's due to mutation, people with TT alleles dont produce certain type of protein that attracts bacteria that causes body odor.

"Most Europeans have wet earwax, because they have at least one copy of the "wet" version of a gene. Just over a million people in the UK have a rarer dry type of earwax, as they have two copies of a different version of the gene (we all have two of every gene, one from our mothers, and one from our fathers). This gene doesn't just define our earwax type. It also holds the code for building the protein that transports sweat out of pores in our armpits, where it attracts the bacteria that cause body odour. Or at least, one version of it does. The lucky "dry earwax" people don't produce the protein, so they don't make the apocrine underarm sweat that attracts bacteria."

“A high percentage of Koreans have the mutation which alters the composition of sweat so that they do not produce body odor”... “Body odor is produced when sweat is broken down by bacteria that live naturally on the skin. Depending on the composition of the sweat, odor may be different or have no smell at all when broken down by bacteria. The mutation does not alter the production of sweat at all, so wetness itself is not affected."


due to their proximity to eastern eurasians.

It's both ENA and ANE in case of South Asians and Central Asians. Outside Siberia, ANE admixture is high in those regions, so it could have also contributed to it. See K7 (https://docs.google.com/spreadsheets/d/1tFAa7oxWpcNN-OdMMjBdb4NeWKG7EkpKMzZJVW2_MME/edit?pref=2&pli=1#gid=1145986956) spreadsheet.

Sika
04-05-2019, 12:49 AM
These are pretty interesting...

CEU Utah samples (North/West Euro ancestry):

CC - 79.9%
CT - 23.2%
TT - 0.9%

They have a lot of CT (mix of CC and TT) alleles. At some point, they must have had TT alleles similar % to Germany.

Kazimiera
04-05-2019, 01:11 AM
I'm CC. I'm waxy and I stink!

Rædwald
04-05-2019, 01:28 AM
I'm C;T

celticdragongod
04-05-2019, 01:28 AM
Unfortunately I do not have this allele. :)

Altaylardan Tunaya
04-05-2019, 02:07 AM
tURAN Stronk

T / T

https://i.imgur.com/oe1Rqae.jpg

Pansarkamrat
04-05-2019, 02:17 AM
Just serched on it looks like i am TT.

Luke35
04-05-2019, 02:37 AM
It's due to mutation, people with TT alleles dont produce certain type of protein that attracts bacteria that causes body odor.

"Most Europeans have wet earwax, because they have at least one copy of the "wet" version of a gene. Just over a million people in the UK have a rarer dry type of earwax, as they have two copies of a different version of the gene (we all have two of every gene, one from our mothers, and one from our fathers). This gene doesn't just define our earwax type. It also holds the code for building the protein that transports sweat out of pores in our armpits, where it attracts the bacteria that cause body odour. Or at least, one version of it does. The lucky "dry earwax" people don't produce the protein, so they don't make the apocrine underarm sweat that attracts bacteria."

“A high percentage of Koreans have the mutation which alters the composition of sweat so that they do not produce body odor”... “Body odor is produced when sweat is broken down by bacteria that live naturally on the skin. Depending on the composition of the sweat, odor may be different or have no smell at all when broken down by bacteria. The mutation does not alter the production of sweat at all, so wetness itself is not affected."



It's both ENA and ANE in case of South Asians and Central Asians. Outside Siberia, ANE admixture is high in those regions, so it could have also contributed to it. See K7 (https://docs.google.com/spreadsheets/d/1tFAa7oxWpcNN-OdMMjBdb4NeWKG7EkpKMzZJVW2_MME/edit?pref=2&pli=1#gid=1145986956) spreadsheet.

Interesting. I actually can get away with not wearing deodorant. However, if it's hot or I am working out, than I do need it. I actually think I sweat less than the average person - especially in my underarms - perhaps this is the bigger factor in why I am less smelly.

Sika
04-07-2019, 11:07 PM
Just serched on it looks like i am TT.

In Finnish samples it peaks at 25%. I think Russians should be closer to this as well.

Carpatz
04-07-2019, 11:22 PM
I have C / T