Is some slight inbreeding any cause for concern?

[Richmondbread]

Doing some finishing touches on my family tree, I came to discover my grandparents were 6th cousins. Which isn't such a big deal. But then my 4th Great grandparents are 1st cousins, and on my mother's tree there is a lot of intermarrying, so much so, that I found "double cousins" on quite a few lines. Would this cause any genetic issues, or is it far enough back in time to not make an issue? Back in Colonial Virginia, there were only so many people around and a lot of people did seem to "keep it in the family". I wonder if maybe some of the mental illness on my mother's side could be attributed to mild inbreeding, but I'm not sure. I turned out pretty normal, though.

[Dick]

https://media1.giphy.com/media/26BRQlqzXTF1WvZjG/giphy.gif

[PaleoEuropean]

Doing some finishing touches on my family tree, I came to discover my grandparents were 6th cousins. Which isn't such a big deal. But then my 4th Great grandparents are 1st cousins, and on my mother's tree there is a lot of intermarrying, so much so, that I found "double cousins" on quite a few lines. Would this cause any genetic issues, or is it far enough back in time to not make an issue? Back in Colonial Virginia, there were only so many people around and a lot of people did seem to "keep it in the family". I wonder if maybe some of the mental illness on my mother's side could be attributed to mild inbreeding, but I'm not sure. I turned out pretty normal, though.

Very common, most villagers married their distant cousins in Europe and the aristocracies married even closer than that a lot of the time. Only becomes a problem when the breeding is too close like siblings/parents and if it's consistently close. Pure bred dogs are are highly inbred, it's how nature selects the most suitable traits sometimes. People in Europe even today practice inbreeding a lot of times without knowing it. Small villages all over Northern Europe are mostly cousins. Inbreeding is misunderstood scientifically. That being said, genetic diversity is just as good, you need fresh genetics added to the pool.

[Leto]

Very common, most villagers married their distant cousins in Europe and the aristocracies married even closer than that a lot of the time. Only becomes a problem when the breeding is too close like siblings/parents and if it's consistently close. Pure bred dogs are are highly inbred, it's how nature selects the most suitable traits sometimes. People in Europe even today practice inbreeding a lot of times without knowing it. Small villages all over Northern Europe are mostly cousins. Inbreeding is misunderstood scientifically. That being said, genetic diversity is just as good, you need fresh genetics added to the pool.
Europeans are probably the least inbred people, the Catholic church and monarchs explicitly forbade marriages between close relatives. On the other hand in the Islamic world it's commonplace even today. There is millions of Arabs, Turks, Kurds, South Asians in the West, yet they import (not all, I know) wives/spouses from their homelands.

[Richmondbread]

Europeans are probably the least inbred people, the Catholic church and monarchs explicitly forbade marriages between close relatives. On the other hand in the Islamic world it's commonplace even today. There is millions of Arabs, Turks, Kurds, South Asians in the West, yet they import (not all, I know) wives/spouses from their homelands.

A lot of the Colonies probably experienced some inbreeding, simply because there weren't enough people to go around. So that is why many White Americans claim Native American. If the English Captain couldn't find another English lady for his wife, he needed to grab a Pocahontas.

[Bellbeaking]

Nope. Negative effects of extensive familiaral inbreeding go pretty quickly once that population stops doing it, so unless your parents are related to each other you are fine. People seem to think inbreeding 'mutates' your gene pool or something, in reality you just have increased chance of coalescence of 'bad' recessive alleles, and this effect compounds as families inbreed generation after generation, but goes away the generation they stop doing it.

[Bigsaul]

Inbreeding is a lot more common in upper classes. People simply marry their relatives to keep the wealth within the family.

[Joso]

If just "slightly" then not.