How well do your muscles perform?

[PaleoEuropean]

I am rs1815739(C;C):
Better performing muscles. Likely sprinter. This genotype indicates better performing muscles, particularly for sprinting and power sports. Fast-twitch muscle fibers are able to produce alpha-actinin-3. Professional sprinters usually have this, although it is less common for endurance athletes.
rs1815739

(C;C) 2.2 Better performing muscles. Likely sprinter.
(C;T) 2.1 Mix of muscle types. Likely sprinter.
(T;T) 2.2 Impaired muscle performance. Likely endurance athlete.

[Senpai]

C;C or C;T
Can't remember which, but I'm definitely built for Sprinting and not endurance.

[PaleoEuropean]

C;C or C;T
Can't remember which, but I'm definitely built for Sprinting and not endurance.

Yea you looks like you keep muscle mass well.

[PaleoEuropean]

Also that shit is very true for me xD. I can sprint absurdly fast and am good at power workouts better than endurance workouts.

[Senpai]

Also that shit is very true for me xD. I can sprint absurdly fast and am good at power workouts better than endurance workouts.

I'm mostly ectomorph, but I hold muscle pretty well when I'm moderately active. I've always been one of the fastest in my friend group as a kid, and excelled in fast sports. I'm also ADHD and slightly Asthmatic, so both tend to lend themselves to me working in short bursts lol.

[paradox]

Muscle Performance

rs1815739TT
Gene: ACTN3

People with your genotype have impaired muscle performance. Likely endurance athlete.

My father's

Muscle Performance

rs1815739CT
Gene: ACTN3

People with your genotype are a mix of muscle types. Likely sprinter.

[Trouble]

c/t

[Lemminkäinen]

CT here.

[Maintenance]

C/T

[frankhammer]

C/C

[Impaler]

C/T.

[andre]

C;C

[SUPREEEEEME]

CT

"Muscles are composed of two major protein filaments: a thick filament composed of the protein myosin and a thin filament composed of the protein actin. Myosin filaments attach to actin via binding sites. Muscle contraction occurs when these filaments slide over one another in a series of repetitive “power strokes” brought about by myosin pulling on these actin-binding sites.

ACTN3 codes the α-actinin-3 protein (ACTN3), a part of the contractile apparatus in the “fast-twitch” muscle fibres that are responsible for rapid muscle contractions. This protein binds to actin and helps give it increased stability during muscle contractions. This allows for a stronger “power stroke” or pull of the myosin filaments on the actin filaments. This, in turn, facilitates a stronger, quicker muscle contraction which is characteristic of fast-twitch muscle fibres.

A genetic variant in the DNA coding for ACTN3 disrupts its production and no ACTN3 is made. This change in the DNA makes those fast-twitch muscles act more like slow-twitch muscles, effectively altering the ratio of fast-to-slow twitch muscle fibres within an individual.

The Single Nucleotide Polymorphism (SNP) rs1815739 can lead to a non-functional ACTN3 gene. The TT genotype results in a shorter, non-functional protein being coded for. In response to this, α-actinin-2 is up-regulated but there are still many studies that find an association between this SNP and physical performance. The CC genotype is associated with increased strength or sprint performance.

We have detected the variant of ACTN3 that produces a fully functional protein.

Population distribution
Both alleles, TT and CC, are common in populations throughout the world, except in Africa where the variant linked with power performance (the 'C' allele) is far more common with a frequency of around 90%.

ACTN3 TT frequency increases with geographic latitude. For example, Sweden, with a latitude of greater than 60 degrees North, has a high TT genotype frequency, whereas Nigeria and Kenya, with latitudes of less than 10 degrees North and South respectively, have a much lower frequency. The ACTN3 genotype frequency has also been compared across ethnic groups. Asians have around 25% TT genotype frequency, Caucasians 18%, Ethiopians 11%, Jamaican and US African Americans 3%, and Kenyans and Nigerians 1%."

"Your genetic results indicate your muscles may posses more fast-twitch characteristics, increasing their maximum strength and power performance. This would give you greater muscular ability to perform heavy weight training, explosive (quick, intense) weight training, jumping, and sprinting activities interspersed with longer rest periods."

"Your muscles may perform best with heavier weights at lower reps."