Neanderthal Gene Protects against covid

[MechtoidAfalouHG]

Reposting from different forum

https://www.nature.com/articles/s41591-021-01281-1

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

Sirui Zhou, Guillaume Butler-Laporte, […]J. Brent Richards
Nature Medicine (2021)Cite this article

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Abstract
To identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility and severity, we undertook a two-sample Mendelian randomization (MR) study, rapidly scanning hundreds of circulating proteins while reducing bias due to reverse causation and confounding. In up to 14,134 cases and 1.2 million controls, we found that an s.d. increase in OAS1 levels was associated with reduced COVID-19 death or ventilation (odds ratio (OR) = 0.54, P = 7 × 10−8), hospitalization (OR = 0.61, P = 8 × 10−8) and susceptibility (OR = 0.78, P = 8 × 10−6). Measuring OAS1 levels in 504 individuals, we found that higher plasma OAS1 levels in a non-infectious state were associated with reduced COVID-19 susceptibility and severity. Further analyses suggested that a Neanderthal isoform of OAS1 in individuals of European ancestry affords this protection. Thus, evidence from MR and a case–control study support a protective role for OAS1 in COVID-19 adverse outcomes. Available pharmacological agents that increase OAS1 levels could be prioritized for drug development.


And the good news is both 23andMe(V3) and FT-DNA measured rs10774671

"It is therefore necessary to have an ancestral allele (G) for that "the protective effect size was particularly large, such that a 50% decrease in the odds of very severe COVID-19 was observed"

I am G/A<blockquote class="imgur-embed-pub" lang="en" data-id="a/jmW7Cmi" data-context="false" ><a href="//imgur.com/a/jmW7Cmi"></a></blockquote><script async src="//s.imgur.com/min/embed.js" charset="utf-8"></script>

[de Burgh II]

https://i.postimg.cc/TYn8GpYm/Untitled.jpg

[Dick]

Covid is white suprematism. Cancel it nao

[MechtoidAfalouHG]

Covid is white suprematism. Cancel it nao

Well its from China so canceling it would be racist towards the Yellows

[Dick]

Well its from China so canceling it would be racist towards the Yellows

Remember when Dr Fraudski said African Americans should get the vaccine first

[de Burgh II]

Covid is white suprematism. Cancel it nao

Covid-19 is natural selection in the process; nature culls people who don't have this immunity/genes and spares people like me and mechtoid19 from the severity of covid-19's virus attack on a person's lungs. That is why most of the Native Americans died out when the European colonialists brought over diseases they weren't used to. Natural selection made most Latinos/Latinas hybridized tri-racials that gives them hybrid vigor.

Hybrid Vigor/Heterosis:


Since the early 1900s, two competing genetic hypotheses, not necessarily mutually exclusive, have been developed to explain hybrid vigor. More recently, an epigenetic component of hybrid vigor has also been established.[11][12]

The genetic dominance hypothesis attributes the superiority of hybrids to the masking of expression of undesirable (deleterious) recessive alleles from one parent by dominant (usually wild-type) alleles from the other (see Complementation (genetics)). It attributes the poor performance of inbred strains to the expression of homozygous deleterious recessive alleles. The genetic overdominance hypothesis states that some combinations of alleles (which can be obtained by crossing two inbred strains) are especially advantageous when paired in a heterozygous individual. This hypothesis is commonly invoked to explain the persistence of some alleles (most famously the Sickle cell trait allele) that are harmful in homozygotes. In normal circumstances, such harmful alleles would be removed from a population through the process of natural selection. Like the dominance hypothesis, it attributes the poor performance of inbred strains to expression of such harmful recessive alleles. In any case, outcross matings provide the benefit of masking deleterious recessive alleles in progeny. This benefit has been proposed to be a major factor in the maintenance of sexual reproduction among eukaryotes, as summarized in the article Evolution of sexual reproduction. [...]

https://en.wikipedia.org/wiki/Heterosis

In layman's terms, by making a person's successive generations more heterogeneous/diverse; one's genetic fitness is enhanced in nature to combat new viruses/ environmental pressures that will force people to adapt to the new environment that they are exposed to.

Each race has their own ecological niche that they were forced to adapt to that determined how they genes were expressed in their current environment. Nevertheless, that is simply how natural selection works when it is controlled under the right circumstances. Modern medicine and the modern welfare state goes against the natural order of natural selection because it takes away nature's ability to weed out maladaptive/"weak" genes such as low-intelligence, mentally-unstable and "criminal" genetics.

Nevertheless, we will have to see nature's plans when it comes in due time....

[Dick]

Covid-19 is natural selection in the process; nature culls people who don't have this immunity/genes and spares people like me and mechtoid19 from the severity of covid-19's virus attack on a person's lungs. That is why most of the Native Americans died out when the European colonialists brought over diseases they weren't used to. Natural selection made most Latinos/Latinas hybridized tri-racials that gives them hybrid vigor.

Hybrid Vigor/Heterosis:



https://en.wikipedia.org/wiki/Heterosis

In layman's terms, by making a person's successive generations more heterogeneous/diverse; one's genetic fitness is enhanced in nature to combat new viruses/ environmental pressures that will force people to adapt to the new environment that they are exposed to.

Each race has their own ecological niche that they were forced to adapt to that determined how they genes were expressed in their current environment. Nevertheless, that is simply how natural selection works when it is controlled under the right circumstances. Modern medicine and the modern welfare state goes against the natural order of natural selection because it takes away nature's ability to weed out maladaptive/"weak" genes such as low-intelligence, mentally-unstable and "criminal" genetics.

Nevertheless, we will have to see nature plans when it comes in due time....
Well now you know where our 23andme results went, to Wuhan.

[de Burgh II]

Well now you know where our 23andme results went, to Wuhan.

Its a fair trade if you ask me; it gives me insight to explore my dna further. Everything in life comes at a cost, you just have to play cards right under the right circumstances.

[Dick]

Its a fair trade if you ask me; it gives me insight to explore my dna further. Everything in life comes at a cost, you just have to play cards right under the right circumstances.

The Jews sold our DNA to the chinks , bro

[de Burgh II]

The Jews sold our DNA to the chinks , bro

The same could be said with Zuckerberg (Jew) with his Asian wife selling your Facebook information to third party companies/sites to the highest bidder...

No matter which way we look at it... in the modern age... we are all equally fucked...

[MechtoidAfalouHG]

The same could be said with Zuckerberg (Jew) with his Asian wife selling your Facebook information to third party companies/sites to the highest bidder...

No matter which way we look at it... in the modern age... we are all equally fucked...

We’re actually more fucked than most people realize. Ever since we picked up a smart phone. Everything we ever did, wrote, looked up, stared at, ect was put into a database where an AI is taking that data to learn everything about you and learn how to predict what you will want,do, even think in the future. This technology is only progressing and you will not be able to fight that which understands you better than you understand yourself.

[de Burgh II]

We’re actually more fucked than most people realize. Ever since we picked up a smart phone. Everything we ever did, wrote, looked up, stared at, ect was put into a database where an AI is taking that data to learn everything about you and learn how to predict what you will want,do, even think in the future. This technology is only progressing and you will not be able to fight that which understands you better than you understand yourself.

I agree 100% because as you put it succinctly, we are all fucked and it will have a major snowball effect from generations to come. My question to you is... what can we do it combat it? I've talked to relatives and newer generations and most of them are fucking (pardon my french) stupid and brainwashed by the media.

A guy I'm subscribed to is accurate about current generations now in a nutshell:


https://www.youtube.com/watch?v=tq0QOEkCHw4

As the years go on, this degenerate bullshit and low-iq crap is rewarding these talent-less retards with millions of dollars that goes against natural selection in every sense of the word. The reason why they are so successful is because of capitalism. Capitalism rewards social media influencers, politicians and athletes/entertainers because capitalism is based on mindless consumerism and anti-intellectual, shallow pursuits. Due to these societal advantages they have; low-iq, mentally unstable people will outbreed high iq, mentally stable people. If this trend continues, society will collapse soon enough.

As you put it succinctly, if this societal trend continues as technology progresses... we will become stupider and more self-destructive that will destroy us all worldwide. Modern medicine and the modern welfare state is undoing everything natural selection work hard to fix...

The only thing we can hope for is a mass extinction event to happen to save us from this future dystopian, mad-max situation that waits for us... the only way against this is to go back to a survivalist, self-sufficient lifestyle to undo all this nonsense...

[MechtoidAfalouHG]

I agree 100% because as you put it succinctly, we are all fucked and it will have a major snowball effect from generations to come. My question to you is... what can we do it combat it? I've talked to relatives and newer generations and most of them are fucking (pardon my french) stupid and brainwashed by the media.

A guy I'm subscribed to is accurate about current generations now in a nutshell:


https://www.youtube.com/watch?v=tq0QOEkCHw4

As the years go on, this degenerate bullshit and low-iq crap is rewarding these talent-less retards with millions of dollars that goes against natural selection in every sense of the word. The reason why they are so successful is because of capitalism. Capitalism rewards social media influencers, politicians and athletes/entertainers because capitalism is based on mindless consumerism and anti-intellectual, shallow pursuits. Due to these societal advantages they have; low-iq, mentally unstable people will outbreed high iq, mentally stable people. If this trend continues, society will collapse soon enough.

As you put it succinctly, if this societal trend continues as technology progresses... we will become stupider and more self-destructive that will destroy us all worldwide. Modern medicine and the modern welfare state is undoing everything natural selection work hard to fix...

The only thing we can hope for is a mass extinction event to happen to save us from this future dystopian, mad-max situation that waits for us... the only way against this is to go back to a survivalist, self-sufficient lifestyle to undo all this nonsense...

This won’t be a problem for very long because the average human is slowly outliving his usefulness (automation) while at the same time not reproducing fast enough for replacement and sustaining the next generation. As well as the elite starting to experiment with viruses, among other things to quell the population even further. The elite , whoever they are, were very smart to socially engineer conditions in which women left their main roles of being mothers for the workplace and to join the rank of tax payers. While at the same time reducing wages in half because there are roughly twice as many workers. This reduced birth rate of the “unwanted” significantly.
From here jobs will slowly be replaced by automation, the average human will be needed less with each advancement. Once the lifestyles of the elite can be sustained without human workers, a virus that actually has a high mortality rate will be released and whatever is left of humanity will be taken care of. Technology will then advance to the point where where the elite will eventually merge with the machines and a new post human era will begin. Probably sounds crazy to most but I believe it will go down this way.

[de Burgh II]

This won’t be a problem for very long because the average human is slowly outliving his usefulness (automation) while at the same time not reproducing fast enough for replacement and sustaining the next generation. As well as the elite starting to experiment with viruses, among other things to quell the population even further. The elite , whoever they are, were very smart to socially engineer conditions in which women left their main roles of being mothers for the workplace and to join the rank of tax payers. While at the same time reducing wages in half because there are roughly twice as many workers. This reduced birth rate of the “unwanted” significantly.
From here jobs will slowly be replaced by automation, the average human will be needed less with each advancement. Once the lifestyles of the elite can be sustained without human workers, a virus that actually has a high mortality rate will be released and whatever is left of humanity will be taken care of. Technology will then advance to the point where where the elite will eventually merge with the machines and a new post human era will begin. Probably sounds crazy to most but I believe it will go down this way.

Isn't this kind of counterintuitive? Basically, what your saying is that the elites (whomever they are affiliated with on a large scale) are doing their own version of hunger games (natural selection) to breed whomever survives in the aftermath to be complacent, low-iq cattle to serve their whims. Take sleepy Joe for example:


https://www.youtube.com/watch?v=TxqzFw8_Ljk

If you want me to be honest with you... most elites are not highly intelligent nor adaptable. The only reason why elites survive is because of their generational wealth and connections in the higher echelons in society. If society collapses and society has no competent workforce to control as you put it... the "automation"; it would become a technocracy that will selectively outbreed and replace the current elites...:


Technocrats are individuals with technical training and occupations who perceive many important societal problems as being solvable with the applied use of technology and related applications. The administrative scientist Gunnar K. A. Njalsson theorizes that technocrats are primarily driven by their cognitive "problem-solution mindsets" and only in part by particular occupational group interests. Their activities and the increasing success of their ideas are thought to be a crucial factor behind the modern spread of technology and the largely ideological concept of the "information society". Technocrats may be distinguished from "econocrats" and "bureaucrats" whose problem-solution mindsets differ from those of the technocrats.[20] [...]

https://en.wikipedia.org/wiki/Technocracy

In other words, the old elites will have to breed with viable candidates whom are technocrats to maintain the complexity and high intellectual strain it would take to maintain said technology....

[cakmir7y]

Good news for me, I've got A/G too. Not so for my wife, she is A/A but vaccinated.

[SouthDutch7991]

I guess this explains why when My entire family tested positive for Covid, we suffered little more than sniffles and my mothers melodrama.