Post Your Level of Lactose Intolerance

[Turul Karom]

I'm an ethnic Hungarian with Germanic shift from my father's side. I have a Turkic/Central Asian genetic background as well. I score every possible lactose intolerance result; this is not surprising since it bothers me horribly every time I eat it. I haven't consumed dairy products for nearly a decade (I stopped in my mid-late teens). What I found interesting is that there seems to be a range of lactose intolerance, and I have read in other threads on this forum that there are people who score one result of lactose intolerance but are able to handle dairy to some degree. Some have theorized that you can train your body to better handle lactose over time when eating dairy. However, it could be that they have more genetic tolerance than intolerance, and the dairy they consume is either hard cheese or other fermented product with lower lactose levels.

I've posted my results below and the relevant SNPs. You can also see my results in the attached image below. Here are the SNPs you can check to see how lactose intolerant you are. Compare the results with my image to see how well you can tolerate dairy products.

Please post your results below, your ethnic background, and if you can tolerate dairy in your real-life experience (if you can, what amounts, types, and frequency). All TA members' results are welcome, but Hungarian members and members with Hungarian or other steppe ancestry are especially encouraged to post their results. A poll is added for additional data. Thanks to everyone who participates!


rs4988235 No risk: A, Risk: G Turul: GG
rs182549 No risk: T, Risk: C Turul: CC
rs41380347 No risk: C, Risk: A Turul: AA
rs41525747 No risk: C, Risk: G Turul: GG
rs145946881 No risk: G, Risk: C Turul: CC
rs869051967 No risk: C, Risk: A Turul: AA

https://i.ibb.co/LYS3BhW/Lactose-intolerance-sequencing-results.png

[Luke35]

rs4988235 - A / G
rs182549 - C / T
rs41380347 - A / A
rs41525747 - G / G
rs145946881 - No genes markers found
rs869051967 - No genes markers found

Looks like rs182549 - C / T saves my butt, as I can in fact drink milk. But not too much. I can have a bowl of breakfast cereal, as long as I go easy on the milk, and don't have anymore later, then I'm okay. But I can certainly overdo it with milk, leads to bad abdominal cramping for me.

Cheese is fine for me, I like it and I don't restrict. But I should work on eating less of it, I don't need the high fat content.

So I would vote mildly intolerant, and it stops me. :)

[Italicus]

I don't know about my SNPs, but I can intake dairy surprisingly well for someone with Levantine (via Roman times) and Chinese ancestry.

[Kaspias]

rs4988235 G/G
rs182549 C/C
rs41380347 A/A
rs41525747 G/G
rs145946881 No genes markers found
rs869051967 No genes markers found

I can't eat cheese and any type of product that includes whey(a piece of biscuit with whey makes me sick whole day). I can't drink milk. The negligence causes serious effects which prevent me to do my daily stuff.

There are exceptions, I can actually eat chocolate that includes some percentage of milk, and also fermented products such as ayran and yogurt, however, it must be limited. If eating too much yogurt, then it will still cause the effects.

These all began in the early 20s, I was drinking daily 1l milk with no problem at all before then.

[Gergő Marosvári]

rs4988235 - G / G
rs182549 - C / C
rs41380347 - A / A
rs41525747 - G / G
rs145946881 - No genes markers found
rs869051967 - No genes markers found

I have absolutely NO idea what these markers mean to be honest.

But YDP says this: People with your genotype are more likely to be lactose intolerant and be unable to digest milk.

Well, "currently" I can drink milk and also I am a huge cheese lover.

[Impaler]

rs4988235 - GG
rs182549 - CC
rs41380347 - AA
rs145946881 - No genes markers found
rs869051967 - No genes markers found

[Ouistreham]

I was born in Normandy, my ancestry is 50% Norman (the rest is Breton and Lorrain), educated in Normandy, I live nearby Normandy, the country of dairy products, butter, creamy sauces and soft cheeses (Camenbert, Bray, Neufchâtel...), I love them all, I drink only whole milk (except when partying, when dark ale and white wine are preferred)...

If I were lactose intolerant I wouldn't survive.

[Insuperable]

rs4988235 - G / G
rs182549 - C / C
rs41380347 - A / A
rs41525747 - G / G
rs145946881 - No genes markers found
rs869051967 - No genes markers found

I drink milk and eat cheese like it's nothing, with no problems. So does my mother and so did my grandparents eat it with no problem until their death.

[Gallop]

Mine

rs4988235_ No results found
rs182549_ No results found
rs41380347_ No results found
rs41525747_ No results found
rs145946881_ No results found
rs869051967_No results found


Father

rs75961395_7e-07e-05 -/-
rs182549_C/T
rs41380347 No results found
rs41525747_No results found
rs145946881_C/C
rs869051967_No results found


God loves me!


:flamenco:

[Kyp]

rs4988235 G/G
rs182549 C/C
rs41380347 A/A
rs41525747 G/G
rs145946881 No genes markers found
rs869051967 No genes markers found

no problems

[Dick]

rs4988235 A / G
rs182549 C / T
rs41380347 A / A
rs41525747 G / G
rs145946881 No genes markers found
rs869051967 No genes markers found

[Roy]

In fact it is being lactose tolerant that is the weird thing.

[Chocolatepug37]

I am not sure if that’s the same as lactose intolerant. I’m just allergic to the milk, period. I didn’t know there were gene markers associated with lactose intolerance. I don’t have that DNA info. Maybe it’s 23 and me that does that info.

[Brás Garcia de Mascarenhas]

rs4988235: A / G
rs182549: C / T
rs41380347: A / A
rs41525747: G / G
rs145946881 No genes markers found
rs869051967 No genes markers found

[Rædwald]

rs4988235 A/A
rs182549 T/T
rs41380347 A/A
rs41525747 G/G
rs145946881 "No genes markers found"
rs869051967 "No genes markers found"

[Flashball]

Mother (50% Sardinian 50% French)
rs4988235 GG (risk)
rs182549 C(risk) T(no risk)
rs41380347 AA (risk)
rs41525747 GG (risk)
rs145946881
rs869051967

She is lactose tolerant (100%)



Father
rs4988235 AA (no risk)
rs182549 TT(no risk)
rs41380347 AA (risk)
rs41525747 GG (risk)
rs145946881 pas dispo
rs869051967 pas dispo

He's lactose tolerant (100%)



Me (75% French 25% Sardinian)
rs4988235 A(no risk) G(risk)
rs182549 TT (no risk)
rs41380347 AA (risk)
rs41525747 GG (risk)
rs145946881 no SNP
rs869051967 no SNP

I'm lactose tolerant (100%)
I drink milk every day mixed with other thing (coffee before, now chicory mixed with milk), I can drink milk alone, as a child I ate goat cheese as much as cow cheese, etc.


Friend (87% french and 12% ukrainian)
rs4988235 GG
rs182549 CC
rs41380347 AA
rs41525747 GG

I don't know if he's lactose tolerant or not, i think he's tolerant.

[Flashball]

My brother in law (half french and half hungarian)
rs4988235 AG
rs182549 CT
rs41380347 AA
rs41525747 GG

[Jana]

rs4988235 A/A
rs182549 T/T
rs41380347 A/A
rs41525747 G/G

Never noticed any problems with milk consumption.

[Defcon2]

rs4988235 AA
rs182549 TT
rs41380347 AA
rs41525747 GG

I'm lactose tolerant.

[Jana]

Stears results:

rs4988235 A/A
rs182549 T/T
rs41380347 A/A
rs41525747 G/G

Also no problems, he consumes dairy products on daily basis.

[PT Tagus]

rs4988235: A/G
rs182549: not determined
rs41380347: A/A
rs41525747: G/G
rs145946881 No genes markers found
rs869051967 No genes markers found

[ANXIETY (ADEPT)]

For me any dairy is fine; milk, cheese, yogurt, but for some reason ice cream doesnt sit right

[SilverKnight]

The first one
---> I have no genetic intolerance and can eat as much dairy as I want.

[Ellethwyn]

I am very intolerant. Thankfully i can at least eat parmesan without any issues.

[Rafael Passoni]

"rs4988235","2","136608646","GG"
"rs182549" No gene Markers found
"rs41380347" No gene markers found
"rs41525747" No gene markers found
"rs145946881" No gene markers found
"rs869051967" No gene markers found
I have never had any problem eating these foods.

[Rostos vilmoskörte]

rs4988235 G / G
rs182549 C / C
rs41380347 A / A
rs41525747 G / G
rs145946881 No marker
rs869051967 No marker

I can't drink or eat dairy except hard cheese which has almost no lactose at all.

[vandor]

I cant live without dairy, cheese, cottage cheese, youghurt, kefir, coffee with milk, no issues, thanks God.

[frankhammer]

A mixed bag

rs4988235 A / G
rs182549 C / T
rs41380347 A / A
rs41525747 G / G

[Hithaeglir]

rs4988235 GG
rs182549 CC
rs41380347 Null
rs41525747 Null
edit
+

rs145946881 Null
rs869051967 Null

The first two markers seem like I might have a high risk of intolerance but I can drink milk without issues :noidea:

[NSXD60]

My lactose intolerant breaking point is laying right underneath the cow's nipple. I would do anything for milk but I won't do that.

[Petalpusher]

s4988235 No risk: A, Risk: G A/A
rs182549 No risk: T, Risk: C T/T
rs41380347 No risk: C, Risk: A A/A
rs41525747 No risk: C, Risk: G G/G
rs145946881 No risk: G, Risk: C no markers
rs869051967 No risk: C, Risk: A no markers

First two are likely more important. I can drink raw milk all day, even used to drink fresh milk from the cows where i grew up at my grandparents.

[Petalpusher]

dp bs

[Roy]

Again I can't find on 23andme that place to check for individual SNPs :picard1: Googling does not help either. I remember though that I am fully lactose intolerant.

[Petalpusher]

Again I can't find on 23andme that place to check for individual SNPs :picard1: Googling does not help either. I remember though that I am fully lactose intolerant.

Try this link or look for "raw data explore"

https://you.23andme.com/tools/data/?query=rs4988235