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View Full Version : Madagascar: Interesting new PCA from 2023 article mapped Malagasians in the Centre-of-Everything



Eugene Finkelstein
03-12-2023, 10:42 PM
Greetings.
Just read a new publication from Genes and thought I'd share it with respectable Apricity audience ^^
https://i.postimg.cc/zvKFBGR0/genes-14-00665-g001.png
Manojlovic Z, Auslander A, Jin Y, Schmidt RJ, Xu Y, Chang S, Song R, Ingles SA, Nunes A, Vavra K, Feigelson D, Rakotoarison S, DiBona M, Magee K, Smile O, Ramamonjisoa A, Magee III W. Genome Analysis Using Whole-Exome Sequencing of Non-Syndromic Cleft Lip and/or Palate from Malagasy Trios Identifies Variants Associated with Cilium-Related Pathways and Asian Genetic Ancestry. Genes. 2023; 14(3):665. https://doi.org/10.3390/genes14030665

Petalpusher
03-12-2023, 10:58 PM
The admix run shows they are simply on an East Asian - African cline, very little Euro (or South Asian). What's more interesting is they are significantly more East Asian than African on average. Some clearly look to have Asiatic influence but i wouldn't have guessed it to be higher than their African.

Eugene Finkelstein
03-14-2023, 01:55 PM
By the way, a little off-topic:
Petalpusher, do you know any population/ethnicity that is tri-mixed in near equal parts of African/West Eurasian (EUR, SAS)/East Asian? Curious theme as for me - to find some human group which could be described as a representation of modern humanity.

Jingle Bell
03-14-2023, 02:06 PM
By the way, a little off-topic:
Petalpusher, do you know any population/ethnicity that is tri-mixed in near equal parts of African/West Eurasian (EUR, SAS)/East Asian? Curious theme as for me - to find some human group which could be described as a representation of modern humanity.

Suriname have a lot of SSA, European ( N and S), Sul Asia and Eastern Asia and some Native.