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02-03-2025, 05:16 PM
Report on the Potential Influence of BolshoyOleniyOstrov on the Formation of Marvele
Introduction
This report examines the potential influence of the population BolshoyOleniyOstrov on the genetic formation of Marvele, a population located in Lithuania. By comparing genetic samples from these two populations and older populations, we seek to determine if BolshoyOleniyOstrov had any significant genetic impact on the development of Marvele.
Methods
Correlation Analysis: Pearson's correlation coefficient was used to assess the genetic similarity between the average principal components (PCs) of BolshoyOleniyOstrov samples and Marvele samples. This correlation value was computed to understand the degree of genetic overlap.
Statistical Testing (t-Tests): Independent t-tests were conducted to compare the means of the key principal components (PC1, PC2, and PC3) between the BolshoyOleniyOstrov and Marvele populations. The tests were aimed at assessing whether there are statistically significant differences in the genetic profiles between these two populations.
Analysis of Variance (ANOVA): ANOVA was employed to determine if there were significant differences in the variance of principal components (PC1, PC2, and PC3) between BolshoyOleniyOstrov and Marvele, which provided insight into the genetic diversity within each population.
Effect Sizes: Effect sizes (Cohen’s d) were calculated to quantify the magnitude of the differences observed in the principal components, helping to interpret the practical significance of the results.
Results
Correlation Between BolshoyOleniyOstrov and Marvele:
The correlation between BolshoyOleniyOstrov and Marvele was low, with values under 0.3 for older BolshoyOleniyOstrov samples.
Correlation values ranged from 0.226 to 0.273 for samples of BolshoyOleniyOstrov that were older than Marvele (e.g., from 1775 BC to 1529 BC).
This suggests that BolshoyOleniyOstrov did not have a direct or strong genetic influence on Marvele.
Comparison with Other Older Samples:
Other older populations (e.g., from the EIA Sargatka and Minino regions) showed a moderate correlation with Marvele (correlation values between 0.29 and 0.38).
These samples showed no strong genetic overlap with Marvele and were not closely linked to BolshoyOleniyOstrov, further suggesting that other factors influenced the genetic makeup of Marvele.
Principal Component Analysis:
The analysis of principal components (PCs) revealed that while there were minor overlaps, the genetic separation between BolshoyOleniyOstrov and Marvele was statistically significant.
This indicates that these two populations evolved independently and did not share a substantial amount of genetic material, further supporting the conclusion that BolshoyOleniyOstrov did not heavily influence Marvele.
Impact of Isolation and Migration:
BolshoyOleniyOstrov was geographically isolated and likely underwent unique genetic adaptations. On the other hand, Marvele had greater contact with southern populations, which led to increased genetic diversity and differentiation from BolshoyOleniyOstrov.
The low correlation values between BolshoyOleniyOstrov and Marvele suggest that migration and interactions with other populations played a much larger role in shaping Marvele’s genetic structure.
Conclusions
BolshoyOleniyOstrov did not have a significant genetic influence on the formation of Marvele. The correlation between the populations is low, and the genetic separation between them is clear, especially in PC1 and PC2.
Geographical isolation and genetic diversity arising from migration and interactions with southern populations likely played a much larger role in shaping the genetic profile of Marvele than BolshoyOleniyOstrov did.
Older populations with some genetic similarities to BolshoyOleniyOstrov also did not show strong genetic overlap with Marvele, further supporting the idea that Marvele's genetic makeup was primarily shaped by other factors.
All available samples from 5000BC to 600AD were used in the study. The key populations studied are:
Russia_BolshoyOleniyOstrov_MBA.AG:BOO001.A0101.AG_ _BC_1790__Cov_56.64%,0.084229,-0.151314,0.119924,0.098192,-0.065858,-0.003068,-0.000235,-0.001385,0.002659,-0.045559,0.031666,-0.008093,0.024678,-0.050095,-0.005836,0.008088,-0.004433,0.005828,-0.003394,0.001501,-0.008235,0.010387,0.003451,-0.008073,-0.002275
Russia_BolshoyOleniyOstrov_MBA.AG:BOO002.A0101.AG_ _BC_1775__Cov_49.23%,0.091058,-0.138112,0.122941,0.106591,-0.062165,0.000558,-0.003525,0.007615,-0.005931,-0.045923,0.037025,-0.01109,0.022299,-0.053673,0.001493,0.007027,-0.004824,0.003294,-0.002263,0.007629,0.004118,0.008037,0.003697,-0.007953,-0.000479
Russia_BolshoyOleniyOstrov_MBA.AG:BOO003.A0101.AG_ _BC_1775__Cov_56.16%,0.09675,-0.129988,0.122187,0.104653,-0.055087,0,-0.003055,0.000692,0.004295,-0.051026,0.035725,-0.009891,0.024083,-0.047342,-0.0019,0.008353,-0.001825,0,-0.001634,0.002126,0.006988,0.004328,0.006902,-0.019159,0.001317
Russia_BolshoyOleniyOstrov_MBA.AG:BOO004.A0101.AG_ _BC_1775__Cov_68.66%,0.091058,-0.145221,0.112382,0.111436,-0.054164,-0.001952,-0.0047,-0.004154,-0.000818,-0.040092,0.030691,-0.012439,0.021258,-0.049269,-0.009908,0.009414,0.000652,-0.004054,-0.006034,-0.004502,0.006738,0.002597,0.003944,-0.010965,-0.000479
Russia_BolshoyOleniyOstrov_MBA.AG:BOO005.A0101.AG_ _BC_1775__Cov_64.71%,0.08992,-0.136081,0.121056,0.114343,-0.060319,-0.00251,-0.00611,-0.005769,-0.003272,-0.041732,0.037187,-0.010641,0.019177,-0.048306,-0.002172,0.006232,-0.003781,0.007095,-0.00264,0.006753,0.002496,0.005935,0.010969,-0.022895,0.003952
Russia_BolshoyOleniyOstrov_MBA.AG:BOO006.A0101.AG_ _BC_1775__Cov_55.40%,0.081953,-0.212246,0.123696,0.086564,-0.075706,-0.010877,0.003525,0.003461,0.001636,-0.040092,0.043358,-0.009292,0.021556,-0.048856,-0.014929,0.001326,-0.000261,0.001394,-0.002388,-0.00075,0.001622,0.007419,0.000246,-0.010604,0.003353
Russia_BolshoyOleniyOstrov_MBA.SG:NEO62.SG__BC_152 9__Cov_79.97%,0.078538,-0.132019,0.114268,0.111113,-0.061858,-0.006136,-0.002115,-0.00923,-0.001636,-0.046288,0.029879,-0.013638,0.016799,-0.045691,-0.005157,0.009149,-0.005737,0.00038,-0.003897,0.005378,-0.006489,0.011005,-0.000123,-0.007832,0.003952
Russia_BolshoyOleniyOstrov_MBA.SG:NEO60.SG__BC_151 7__Cov_33.23%,0.084229,-0.164516,0.115022,0.094962,-0.071398,-0.013108,0.003995,-0.004154,-0.000409,-0.03262,0.033777,-0.014087,0.014717,-0.054086,-0.004207,0.002917,-0.00326,0.000507,-0.004399,0.012131,0.013726,0.000124,-0.002958,-0.010965,-0.007784
Lithuania_Marvele_Roman.SG:R10830.SG__AD_438__Cov_ 55.32%,0.129758,0.128972,0.100314,0.096254,0.05231 7,0.046017,0.022326,0.017076,0.001432,-0.038816,-0.001786,-0.018733,0.036571,0.039635,-0.019815,-0.007558,-0.00665,0.006208,0.004148,0.003752,-0.008485,-0.006306,0.015406,-0.025907,0.005269
Lithuania_Marvele_Roman.SG:R10832.SG__AD_475__Cov_ 47.34%,0.142279,0.125926,0.107857,0.093993,0.05539 5,0.04016,0.008695,0.018461,0.00634,-0.044466,-0.013641,-0.016635,0.026313,0.029314,-0.007057,-0.001458,0.005607,-0.007095,-0.000377,0.017508,-0.002745,-0.005935,0.012448,-0.014701,-0.005748
Lithuania_Marvele_Roman.SG:R10836.SG__AD_475__Cov_ 49.41%,0.133173,0.127957,0.091263,0.098515,0.04770 1,0.038208,0.016216,0.017538,0.004704,-0.042643,-0.009094,-0.012139,0.033151,0.046792,-0.006379,-0.007027,-0.010561,-0.00152,-0.001634,0.000125,-0.00574,-0.00915,0.003944,-0.018918,-0.003113
Lithuania_Marvele_Roman.SG:R10838.SG__AD_475__Cov_ 56.44%,0.136588,0.123895,0.093149,0.10756,0.047701 ,0.039881,0.011751,0.011999,-0.009204,-0.045012,-0.004872,-0.016635,0.029881,0.031516,-0.013029,0.005436,0.015125,-0.003167,0.004022,0.007629,-0.000125,-0.000618,0.002711,-0.008314,-0.003113
Introduction
This report examines the potential influence of the population BolshoyOleniyOstrov on the genetic formation of Marvele, a population located in Lithuania. By comparing genetic samples from these two populations and older populations, we seek to determine if BolshoyOleniyOstrov had any significant genetic impact on the development of Marvele.
Methods
Correlation Analysis: Pearson's correlation coefficient was used to assess the genetic similarity between the average principal components (PCs) of BolshoyOleniyOstrov samples and Marvele samples. This correlation value was computed to understand the degree of genetic overlap.
Statistical Testing (t-Tests): Independent t-tests were conducted to compare the means of the key principal components (PC1, PC2, and PC3) between the BolshoyOleniyOstrov and Marvele populations. The tests were aimed at assessing whether there are statistically significant differences in the genetic profiles between these two populations.
Analysis of Variance (ANOVA): ANOVA was employed to determine if there were significant differences in the variance of principal components (PC1, PC2, and PC3) between BolshoyOleniyOstrov and Marvele, which provided insight into the genetic diversity within each population.
Effect Sizes: Effect sizes (Cohen’s d) were calculated to quantify the magnitude of the differences observed in the principal components, helping to interpret the practical significance of the results.
Results
Correlation Between BolshoyOleniyOstrov and Marvele:
The correlation between BolshoyOleniyOstrov and Marvele was low, with values under 0.3 for older BolshoyOleniyOstrov samples.
Correlation values ranged from 0.226 to 0.273 for samples of BolshoyOleniyOstrov that were older than Marvele (e.g., from 1775 BC to 1529 BC).
This suggests that BolshoyOleniyOstrov did not have a direct or strong genetic influence on Marvele.
Comparison with Other Older Samples:
Other older populations (e.g., from the EIA Sargatka and Minino regions) showed a moderate correlation with Marvele (correlation values between 0.29 and 0.38).
These samples showed no strong genetic overlap with Marvele and were not closely linked to BolshoyOleniyOstrov, further suggesting that other factors influenced the genetic makeup of Marvele.
Principal Component Analysis:
The analysis of principal components (PCs) revealed that while there were minor overlaps, the genetic separation between BolshoyOleniyOstrov and Marvele was statistically significant.
This indicates that these two populations evolved independently and did not share a substantial amount of genetic material, further supporting the conclusion that BolshoyOleniyOstrov did not heavily influence Marvele.
Impact of Isolation and Migration:
BolshoyOleniyOstrov was geographically isolated and likely underwent unique genetic adaptations. On the other hand, Marvele had greater contact with southern populations, which led to increased genetic diversity and differentiation from BolshoyOleniyOstrov.
The low correlation values between BolshoyOleniyOstrov and Marvele suggest that migration and interactions with other populations played a much larger role in shaping Marvele’s genetic structure.
Conclusions
BolshoyOleniyOstrov did not have a significant genetic influence on the formation of Marvele. The correlation between the populations is low, and the genetic separation between them is clear, especially in PC1 and PC2.
Geographical isolation and genetic diversity arising from migration and interactions with southern populations likely played a much larger role in shaping the genetic profile of Marvele than BolshoyOleniyOstrov did.
Older populations with some genetic similarities to BolshoyOleniyOstrov also did not show strong genetic overlap with Marvele, further supporting the idea that Marvele's genetic makeup was primarily shaped by other factors.
All available samples from 5000BC to 600AD were used in the study. The key populations studied are:
Russia_BolshoyOleniyOstrov_MBA.AG:BOO001.A0101.AG_ _BC_1790__Cov_56.64%,0.084229,-0.151314,0.119924,0.098192,-0.065858,-0.003068,-0.000235,-0.001385,0.002659,-0.045559,0.031666,-0.008093,0.024678,-0.050095,-0.005836,0.008088,-0.004433,0.005828,-0.003394,0.001501,-0.008235,0.010387,0.003451,-0.008073,-0.002275
Russia_BolshoyOleniyOstrov_MBA.AG:BOO002.A0101.AG_ _BC_1775__Cov_49.23%,0.091058,-0.138112,0.122941,0.106591,-0.062165,0.000558,-0.003525,0.007615,-0.005931,-0.045923,0.037025,-0.01109,0.022299,-0.053673,0.001493,0.007027,-0.004824,0.003294,-0.002263,0.007629,0.004118,0.008037,0.003697,-0.007953,-0.000479
Russia_BolshoyOleniyOstrov_MBA.AG:BOO003.A0101.AG_ _BC_1775__Cov_56.16%,0.09675,-0.129988,0.122187,0.104653,-0.055087,0,-0.003055,0.000692,0.004295,-0.051026,0.035725,-0.009891,0.024083,-0.047342,-0.0019,0.008353,-0.001825,0,-0.001634,0.002126,0.006988,0.004328,0.006902,-0.019159,0.001317
Russia_BolshoyOleniyOstrov_MBA.AG:BOO004.A0101.AG_ _BC_1775__Cov_68.66%,0.091058,-0.145221,0.112382,0.111436,-0.054164,-0.001952,-0.0047,-0.004154,-0.000818,-0.040092,0.030691,-0.012439,0.021258,-0.049269,-0.009908,0.009414,0.000652,-0.004054,-0.006034,-0.004502,0.006738,0.002597,0.003944,-0.010965,-0.000479
Russia_BolshoyOleniyOstrov_MBA.AG:BOO005.A0101.AG_ _BC_1775__Cov_64.71%,0.08992,-0.136081,0.121056,0.114343,-0.060319,-0.00251,-0.00611,-0.005769,-0.003272,-0.041732,0.037187,-0.010641,0.019177,-0.048306,-0.002172,0.006232,-0.003781,0.007095,-0.00264,0.006753,0.002496,0.005935,0.010969,-0.022895,0.003952
Russia_BolshoyOleniyOstrov_MBA.AG:BOO006.A0101.AG_ _BC_1775__Cov_55.40%,0.081953,-0.212246,0.123696,0.086564,-0.075706,-0.010877,0.003525,0.003461,0.001636,-0.040092,0.043358,-0.009292,0.021556,-0.048856,-0.014929,0.001326,-0.000261,0.001394,-0.002388,-0.00075,0.001622,0.007419,0.000246,-0.010604,0.003353
Russia_BolshoyOleniyOstrov_MBA.SG:NEO62.SG__BC_152 9__Cov_79.97%,0.078538,-0.132019,0.114268,0.111113,-0.061858,-0.006136,-0.002115,-0.00923,-0.001636,-0.046288,0.029879,-0.013638,0.016799,-0.045691,-0.005157,0.009149,-0.005737,0.00038,-0.003897,0.005378,-0.006489,0.011005,-0.000123,-0.007832,0.003952
Russia_BolshoyOleniyOstrov_MBA.SG:NEO60.SG__BC_151 7__Cov_33.23%,0.084229,-0.164516,0.115022,0.094962,-0.071398,-0.013108,0.003995,-0.004154,-0.000409,-0.03262,0.033777,-0.014087,0.014717,-0.054086,-0.004207,0.002917,-0.00326,0.000507,-0.004399,0.012131,0.013726,0.000124,-0.002958,-0.010965,-0.007784
Lithuania_Marvele_Roman.SG:R10830.SG__AD_438__Cov_ 55.32%,0.129758,0.128972,0.100314,0.096254,0.05231 7,0.046017,0.022326,0.017076,0.001432,-0.038816,-0.001786,-0.018733,0.036571,0.039635,-0.019815,-0.007558,-0.00665,0.006208,0.004148,0.003752,-0.008485,-0.006306,0.015406,-0.025907,0.005269
Lithuania_Marvele_Roman.SG:R10832.SG__AD_475__Cov_ 47.34%,0.142279,0.125926,0.107857,0.093993,0.05539 5,0.04016,0.008695,0.018461,0.00634,-0.044466,-0.013641,-0.016635,0.026313,0.029314,-0.007057,-0.001458,0.005607,-0.007095,-0.000377,0.017508,-0.002745,-0.005935,0.012448,-0.014701,-0.005748
Lithuania_Marvele_Roman.SG:R10836.SG__AD_475__Cov_ 49.41%,0.133173,0.127957,0.091263,0.098515,0.04770 1,0.038208,0.016216,0.017538,0.004704,-0.042643,-0.009094,-0.012139,0.033151,0.046792,-0.006379,-0.007027,-0.010561,-0.00152,-0.001634,0.000125,-0.00574,-0.00915,0.003944,-0.018918,-0.003113
Lithuania_Marvele_Roman.SG:R10838.SG__AD_475__Cov_ 56.44%,0.136588,0.123895,0.093149,0.10756,0.047701 ,0.039881,0.011751,0.011999,-0.009204,-0.045012,-0.004872,-0.016635,0.029881,0.031516,-0.013029,0.005436,0.015125,-0.003167,0.004022,0.007629,-0.000125,-0.000618,0.002711,-0.008314,-0.003113