North Europe, genome study

[Brännvin]

Excelent, very recent study about north Europeans compared to eachother.

Genome-Wide Analysis of Single Nucleotide Polymorphisms Uncovers Population Structure in Northern Europe (http://www.plosone.org/article/info:doi/10.1371/journal.pone.0003519)

Source: 1 Department of Medical Genetics, University of Helsinki, Helsinki, Finland, 2 Finnish Genome Center, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, 3 Department of Biosciences and Nutrition, Karolinska Institutet, and Clinical Research Centre, Karolinska University Hospital, Huddinge, Sweden, 4 Department of Neurology, Umeå University Hospital, University of Umeå, Umeå, Sweden, 5 Popgen Biobank, Institute for Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany, 6 Finnish Red Cross Blood Transfusion Center, Helsinki, Finland, 7 Department of Medical Genetics, University of Turku, Turku, Finland, 8 Department of General Internal Medicine, Institute for Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany, 9 Folkhälsan Institute of Genetics, Biomedicum Helsinki, Helsinki, Finland

For those who believe in David Faux obscure fiction I don't recommend reading this study ;)

[Lenny]

I will serve as the voice of the dense-academic-language illiterate and ask you to summarize the main points, please.

Whenever I try to read those reports my head starts to spin and I don't really understand anything.:(

[lei.talk]

...I don't recommend reading this study ;)doctor david k. faux (http://www.davidkfaux.org/)?

why not?

[Brännvin]

I will serve as the voice of the dense-academic-language illiterate and ask you to summarize the main points, please.

Whenever I try to read those reports my head starts to spin and I don't really understand anything.:(

I do not think the language is so difficult as do you claim so long as the study aims to posted on plosone.org (http://www.plosone.org) this open to the public..

Some points very clear to me that rebate any pseudo-study that was posted in this forum


In this study, we analysed almost 250,000 SNPs from a total of 945 samples from Eastern and Western Finland, Sweden, Northern Germany and Great Britain complemented with HapMap data. Small but statistically significant differences were observed between the European populations (FST = 0.0040, p<10−4), also between Eastern and Western Finland (FST = 0.0032, p<10−3).


The Germans and British were less differentiated than the Swedes, Western Finns and especially the Eastern Finns who also showed other signs of genetic drift. This is likely caused by the later founding of the northern populations, together with subsequent founder and bottleneck effects, and a smaller population size.


The population history of Northern Europe has been reviewed earlier by several authors. The settlement of the Baltic Sea region advanced rapidly after the Ice Age, beginning about 14,000 BC in Northern Germany and 10,000 BC in Finland. All the populations have their roots mainly in Central Europe.

The graph showing the distance between populations almost all within the same parameter, the only ones who suffer a very small differentiation are the Eastern Finns, if you read the study that you will understand the why, the authors make it clear already in the introduction.

http://www.plosone.org/article/fetchObject.action?uri=info%3Adoi%2F10.1371%2Fjour nal.pone.0003519.g007&representation=PNG_M



By the way, the authors of study talks about drifts and bottleneck effects in Northern Europe in different degrees, it was caused by the later founding of the northern populations, migration after the last ice age by central europeans hunter gatherer and their insulation when compared to Central Europe.

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To understand it better you can also check this study as a complement.
Migration Waves to the Baltic Sea Region (http://www.ncbi.nlm.nih.gov/pubmed/18294359)

http://i43.tinypic.com/eq5k4i.jpg

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It seems that this study has already been posted here, oh sorry adms and mods :(
http://www.theapricity.com/forum/showthread.php?t=135