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View Full Version : Ötzi the Iceman's Autosomal Dna



Behrouz
09-20-2013, 03:44 PM
http://en.wikipedia.org/wiki/%C3%96tzi

On 19 September 1991, Ötzi was found by two German tourists from Nuremberg, Helmut and Erika Simon, at 3,210 metres (10,530 ft) on the east ridge of the Fineilspitze in the Ötztal Alps on the Austrian–Italian border, while walking off the path between the mountain passes Hauslabjoch and Tisenjoch. They believed that the body was of a recently deceased mountaineer.[5] The next day, a mountain gendarme and the keeper of the nearby Similaunhütte first attempted to remove the body, which was frozen in ice below the torso, using a pneumatic drill and ice-axes, but had to give up due to bad weather. The next day, eight groups visited the site, amongst whom happened to be the famous mountaineers Hans Kammerlander and Reinhold Messner. The body was semi-officially extracted on 22 September and officially salvaged the following day. It was transported to the University of Innsbruck, where it was recognized to be primeval the same day.[6]
At the Treaty of Saint-Germain-en-Laye (1919), the border of Austria and Italy was defined as the watershed of the rivers Inn and Etsch, and Ötzi's find site drains to the Austrian side. However, the border veers slightly away from the watershed, and surveys in October 1991 showed that the body had been located 92.56 metres (101 yd) inside Italian territoryCoordinates: 46°46′45.8″N 10°50′25.1″E.[7] The province of South Tyrol therefore claimed property rights, but agreed to let Innsbruck University finish their scientific examinations. Since 1998 it has been on display at the South Tyrol Museum of Archaeology in Bolzano, the capital of South Tyrol.


Ötzi reconstruction
http://21stoleti.cz/wp-content/uploads/otzi-reconstruction-body.jpg



Genetic analysis
A group of scientists have sequenced Ötzi's full genome and the report was published on 28 February 2012.[3][31] The Y-DNA of Ötzi belongs to a subclade of G defined by the SNPs M201, P287, P15, L223 and L91 (G-L91, ISOGG G2a2b, former "G2a4"). He was not typed for any of the subclades downstreaming from G-L91. G-L91 is now mostly found in South Corsica.

Analysis of his mitochondrial DNA has shown that Ötzi belongs to the K1 subclade, but cannot be categorized into any of the three modern branches of that subclade (K1a, K1b or K1c). The new subclade has provisionally been named K1ö for Ötzi.[32] Multiplex assay study was able to confirm that the Iceman's mtDNA belongs to a new European mtDNA clade with a very limited distribution amongst modern data sets.[33]

By autosomal DNA he is most closely related to southern Europeans, particularly geographically isolated populations of Sardinia and Corsica.[34][35]

DNA analysis also showed him at high risk of atherosclerosis, lactose intolerance, and the presence of the DNA sequence of Borrelia burgdorferi, making him the earliest known human with Lyme disease.[36]
A 2012 paper by paleoanthropologist John Hawks suggests that Ötzi had a higher degree of Neanderthal ancestry than modern Europeans.[37]




Does anyone know where can i find his autosomal dna results?

Corvus
09-20-2013, 03:47 PM
He looks like a typical Northern Italian or Western Austrian. With modern clothes he would not stand out.

Graham
09-20-2013, 04:00 PM
http://dienekes.blogspot.co.uk/2012/03/first-look-at-genome-of-tyrolean-iceman.html

Dienkes done his own run, if you are interested.

http://1.bp.blogspot.com/-HoUhBMh4TlY/T1iI6XfRqiI/AAAAAAAAEkk/ghGPRkUJrWs/s1600/iceman_genome.jpg

Behrouz
09-20-2013, 04:09 PM
http://dienekes.blogspot.co.uk/2012/03/first-look-at-genome-of-tyrolean-iceman.html

Dienkes done his own run, if you are interested.

http://1.bp.blogspot.com/-HoUhBMh4TlY/T1iI6XfRqiI/AAAAAAAAEkk/ghGPRkUJrWs/s1600/iceman_genome.jpg

Thanks.



Here is the Iceman's autosomal dna according to blog owner

https://docs.google.com/spreadsheet/ccc?key=0ArJDEoCgzRKedHo3UWw0M0Y2dWFBeFI3bGZEdTNRO EE#gid=1

Gedrosia 0
Siberian 0
Northwest_African 5.7
South_Asian 1.5
Atlantic_Med 57.7
Caucasus 22.3
North_European 0
Southeast_Asian 2
East_African 2.4
East_Asian 0.7
Southwest_Asian 7.6
West_African 0

Gaston
09-21-2013, 10:22 AM
Ötzi's genome reveals what the southern Alps were like at his time: less North European (and less European as a whole), even less than Sardinians.

Fire Haired
09-21-2013, 05:51 PM
http://www.theapricity.com/forum/attachment.php?attachmentid=37641&d=1379785852 http://www.theapricity.com/forum/attachment.php?attachmentid=37642&d=1379785897 http://www.theapricity.com/forum/attachment.php?attachmentid=37643&d=1379785905