Fennoscandia Biographic Project(Scandinavian genetics)

This is a project started by Anders Pålsen from DNAforums and it currently have 20 participantes(7 Swedes, 5 Norwegians, 5 Finns and 3 Saami)


BGA Local

D1-2
http://img215.imageshack.us/img215/9...rdroundd12.jpg

D1-3
http://img138.imageshack.us/img138/7...rdroundd13.jpg

D1-4
http://img52.imageshack.us/img52/595...rdroundd14.jpg


BGA regional

D1-2
http://img801.imageshack.us/img801/4...irdroundd1.jpg

D1-3
http://img63.imageshack.us/img63/488...irdroundd1.jpg

D1-4
http://img36.imageshack.us/img36/488...irdroundd1.jpg

SA - Saami
SWE - Swedes
NO - Norwegians
FI - Finns

Quote:

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In all the local (Fennoscandia) plots the norwegian/swedes, finnish and saami all clusters seperate in all 4 dimensions. In the regional view including three reference populations all the local groups cluster seperate from each other but the swedish/norwegian and the finns in several dimensions have some overlap or are very close to the reference populations.

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*
I'm NO4

The labeling of the Swedes in the last two plots are wrong, here are the correct ones:
http://img651.imageshack.us/img651/6...lthirdroun.jpg
http://img246.imageshack.us/img246/6...lthirdroun.jpg

http://img256.imageshack.us/img256/1...egionalthi.jpg


* I think SWE7 must be a Finn or have very recent Finnish ancestry.

Better and update admixture plots(I'm NO4)
http://img818.imageshack.us/img818/9...r4k4update.jpg
http://img593.imageshack.us/img593/5...veragesr4k.jpg

clusters according to the project leader

Serie4 - Finnish and Saami
Serie3 - Central Europe and France
Serie2 - Lithuanian and Belorussian
Serie1 - Orcadian

Admixture sheets:
http://img530.imageshack.us/img530/7...egionalk2k.jpg
http://img19.imageshack.us/img19/380...regionalr5.jpg

Quote:

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ADMIXTURE:

- At K2 or assuming two populations Europe is split into a southern (RED) and northern (BLUE) part with the Sardinians, Cypriots and the Caucasus populations cleary at the southern extreme while the Finns, Saami and the Chuvashes at the northern extreme. North in this context appears to point north-east geographically.

- At K3 or assuming three populations Europe is splitt into 1) south-east Europe populations (BLUE) the the Georgians at the extreme 2) south-west Europe populations (GREEN) with the Sardinians at the extreme 3) north/north-east Europe populations (RED) with the Saami at the extreme.

- At K4 or assuming four populations Europe is splitt into 1) Lithuanians at the extreme (BLUE) 2) Chuvasshes at the extreme (PINK) 3) Sardinians at the extreme (RED) 4) Georgians at the extreme (GREEN).

- At K5 or assuming four populations Europe splitt into 1) Basque at the extreme (RED) 2) Chuvashes at the extreme (PINK) 3) Lithuanians at the extreme (CYAN) 4) Sardinians at the extreme (BLUE) 5) Georgians at the extreme (GREEN).

COMMENT: At the highest K=5 the ADMIXTURE result *alone* seem to suggest that Norwegians, Swedes, Finna and Saami main ancestry is "Lithuanian" but that Finns and especially the Saami have a considerable "Chuvash" influences.


MDS-PLOTS:

- D1-2: The Norwegian and Swedish common clusters together with Belorussians and Lithuanians appear to bridge the space between Orcadians/French and Finns and Volgoda-Russians. The Saami appears to go further past the latter cluster outside towards the Chuvash. The Hungarians appear to neighbour the swedish/norwegian cluster to the upper-right.
- D1-3: The same story as above, but here the Chuvash share the far lower part of the plot with the Sardinians even the distances are large. Also here the Saami appear to pull from the Russians/Finns toward the Chuvashes. In the earlier plot the Chuvashes shared the higher part of the plot with Cacausus populations even the distances where large. The Lithuanians and Belorussians appear to seperate further lower away from the Finns and the Russians.
- D1-4: The same as above.
- D1-5: The Finns appears to have seperatet from the Russian and appears to pull toward the Saami who are alone at the extreme lower-left of the plot. Else much the same as above.
- D1-6: The Finns cluster with the Chuvashes with the Norwegian/Swedish cluster to the right. Russians and Lithuanians below. Saami alone at the upper-left extreme.
- D1-7: The Finns and the Saami appears to cluster alone to the lower-left. Norwegian-Swedish cluster partly with Belorussians/Orcadians.
- D1-8: Mostly the same as above.
- D1-9: Mostly the same as above.

COMMENT: The plots appears to show a more complex picture of the ancestry and relationship than the ADMIXTURE plots. In the lower dimensions the Saami appears to pull toward the Chuvashes but seem to seperate clearly often togheter alone with Finns in higher dimensions. Norwegians and Swedes appears mostly as expected to bridge between the more western populations with the more eastern.

DIST GRAPH:

The graph shows the average distance between populations seen from the four nationalities Norwegians, Swedish, Finns and Saami.

- Norwegians are more similar too Swedes, Belorussians, Orcadians and Lithuanians than themself (!). (Yes I have checked for errors).
- Swedes closest relatives are the Norwegians, Lithuanians and Belorussians. The most distant the Chuvashes, Cypriots and the Georgians.
- Finns closest relatives are the Lithuanians, Swedes and the Belorussians. The most distant are the Cypriots, Adigey and the Chuvashes.
- The Saamis clostest relatives are the Finns, Swedes and the Belorussians. The least distant the Cypriots, Armenians and the Georgians.
- There is very high correlation in the DIST plots between Norwegians and Swedes at 0.9842, then the Finns-Swedes at 0.9387, then Finns-Swedes at 0.9099, then Saami-Finns at 0.725, then Saami-Swedes at 0.511 and finally Saami-Norwegians at 0.4531.
- Saami appears to have consistently much lower genetic affinity with all other populations than the other three. The exception is to the Chuvashes where all appear to have somewhat similar genetic distance.
- Saami affiliation with continental and especially southern European populations are much smaller than the others.

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MDS-PLOTS:
http://img80.imageshack.us/img80/799...egionald12.jpg
http://img26.imageshack.us/img26/168...egionald13.jpg
http://img98.imageshack.us/img98/807...egionald14.jpg
http://img339.imageshack.us/img339/8...egionald15.jpg
http://img208.imageshack.us/img208/1...egionald16.jpg
http://img508.imageshack.us/img508/1...egionald17.jpg
http://img339.imageshack.us/img339/1...egionald18.jpg
http://img593.imageshack.us/img593/5...egionald19.jpg

I'm NO4 and seem fairly vanilla Scandinavian, but it seems NO6 and NO7 are clear outliners and cluster close to the SA(Saami)

http://img196.imageshack.us/img196/4...nalysisd12.jpg
http://img851.imageshack.us/img851/5...nalysisd13.jpg
http://img29.imageshack.us/img29/484...nalysisd14.jpg

Quote:

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Whats new?

- 7 new persons, where 1 is an Estonian.

Results?

- Much the same as earlier. Finns and Saami cluster clearly seperatly from Swedes and Norwegians who mostly overlap each other.
- The Estonian ES1 appears to cluster close to a Finland-Swede and not with other Finns.
- New participant SWE11 appears to deviate away from the Swedish/Norwegian clusters towards mostly Finns and maybe a little towards the Saami cluster.

Whats next?

- Regional MDS plots and ADMIXTURE graphs.
- Genetic distances
- Shared segments

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I'm begining to become a bit sceptical about this project.

In LAMP 2.5 I have a very small Finnish segment, rest is Norwegian
http://4.bp.blogspot.com/-952RqqemXP...600/LAMP25.jpg
Purple - Finnish
Red - Swedish
Blue - Norwegian
Green - Saami

Admixture, I'm 100% Norwegian
http://2.bp.blogspot.com/-jJujW_8XwH.../ADMIXTURE.jpg
Red - Finnish
Blue - Norwegian
Purple - Swedish
Green - Saami

The result looks a bit faulty...

Is it still room for more participants?

http://i.imgur.com/Xc662.gif

My position is a bit hard to spot, but I'm NO4 above SWE15

According to the Feenoscandia blog - SWE7, SWE11 and NO7 are of South Saami background.

Quote:

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About the South Saami samples: SWE7 is confirmed at least partly of Saami background but not of North Saami background. SWE11 have also some geneological confirmed minor Saami background and have most of the origin from current and earlier known non-North-Saami areas. No information is known about NO7.

As comparisment NO6 who have geogaphical origin in the North-Saami area seperate very clearly from NO7, SWE7 and SWE11 by pulling straight at the North-Saami cluster (SA1-SA4) and appearing immediate between the Scandinavain and North-Saami cluster demonstrating that the Saami origin is different for NO7, SWE7 and SWE11.

So apparantly SWE7, SWE11 and NO7 have South-Saami background

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It was a bit confusing that they were not labelled as SA like the North Saami participants.