Quote:
Monday, April 23, 2012
Eurogenes ADMIXTURE utilities at Gedmatch
Gedmatch now features a series of ancestry tests based on my experiments with the ADMIXTURE software. The K9 to K12 are basically part of a single package, and specifically designed for people with recent ancestry from north of the Alps and Carpathians. However, the K9 will be useful for many other individuals. Also, I'll be sending the Hunter Gatherer vs. Farmer allele frequencies to Jon at Gedmatch next week, and that test pretty much covers the entire planet.
The K9 to K12 tests don't suffer from the usual "calculator effect", whereby project members get somewhat different scores from non-members of exactly the same ancestry (the K12b still suffers from this effect, but I'll fix that soon). In other words, all results are directly comparable, and I encourage all users to swap notes vigorously. However, it's important to understand that you won't see dramatic differences in the levels of the inta-North European components. That's because they're largely based on very similar allele frequencies, and separated by low Fst (genetic) distances. Indeed, note the progression from one North European cluster at K9, to four at K12 (North Sea, South Baltic, Volga-Ural and Western European). Generally speaking, the four northern clusters at K12 can be thought of as a subset of the K9 cluster.
Thus, if you're looking for a fairly clean cut summation of your ancestry, then take the results from K9, where genetic differentiation between the clusters is greatest. But I think the K10 to K12 are more useful as genome and chromosome paintings, and that's precisely because they're not as clean cut. As a result, much of your genome won't be covered in just one color, but in a mosaic of colors. Studying these patterns at local level, and cross checking the information with other results, like Ancestry Finder data from 23andMe, might be a useful way of pinpointing segments from very specific parts of Europe.
I'll post more details about the K9 to K12 clusters, including frequencies in various populations, Fst (genetic) distance tables, and hopefully maps, at a later date. So please check this post for updates within a few days.