You've been lied to about Globular Amphora Culture

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Originally Posted by Tilaratch

Under his tool samples with heavy NW euro ancestry like British, Scandinavians, and Finns tend to strongly score white on average. Balto-Slavs are more variable. In that population sense it is not surprising that Vessna as a Belorussian might strongly score olive. There are NW Europeans who have darker skin than Vessna but nevertheless score white with AndreiDNA’s tool. Since skin pigmentation is possibly the most polygenic it might reflect genetic cluster more and individual appearance less than other predictions.

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The reason Vessna scores olive for skin color is because of her HERC2 genotype. If she was homozygous there, instead of heterozygous, she'd score white skin.
HERC2 is strongly tied to skin color by GWAS. It's one of the most reliable ways of predicting skin shade in europeans, who pretty much unanimously have derived SLC24A5 and SLC45A2. But try explaining that to her... Her goal is badmouthing my tool, that's the reason she purchased the reports in the first place. She and her buddies here dont GAF about the genetics of skin color.

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Originally Posted by AndreiDNA

The reason Vessna scores olive for skin color is because of her HERC2 genotype. If she was homozygous there, instead of heterozygous, she'd score white skin.
HERC2 is strongly tied to skin color by GWAS. It's one of the most reliable ways of predicting skin shade in europeans, who pretty much unanimously have derived SLC24A5 and SLC45A2. But try explaining that to her... Her goal is badmouthing my tool, that's the reason she purchased the reports in the first place. She and her buddies here dont GAF about the genetics of skin color.

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HERC2 is the gene associated with eye colour, not skin colour
SNPs, rs916977 and rs12913832

I am heterozygous for both of these SNPs
As Vessna has hazel-green eyes I'd imagine she would be heterozygous for these SNPs too
It wouldn't affect her skin colour

SLC24A5 and SLC45A2 are the genes associated with skin colour....the derived SNPs give Europeans light skin

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Originally Posted by Mopi of the Julii

HERC2 is the gene associated with eye colour, not skin colour
SNPs, rs916977 and rs12913832

I am heterozygous for both of these SNPs
As Vessna has hazel-green eyes I'd imagine she would be heterozygous for these SNPs too
It wouldn't affect her skin colour

SLC24A5 and SLC45A2 are the genes associated with skin colour....the derived SNPs give Europeans light skin

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go through these GWAS studies.
and type in "HERC2" into "Mapped Gene"
https://www.ebi.ac.uk/gwas/efotraits/OBA_VT0002095

They very much do impact skin color. One of the biggest contributors to it in fact.
Attachment 148674

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Originally Posted by Mopi of the Julii

HERC2 is the gene associated with eye colour, not skin colour
SNPs, rs916977 and rs12913832

I am heterozygous for both of these SNPs
As Vessna has hazel-green eyes I'd imagine she would be heterozygous for these SNPs too
It wouldn't affect her skin colour

SLC24A5 and SLC45A2 are the genes associated with skin colour....the derived SNPs give Europeans light skin

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Aside from SLC45A2, SLC24A5, HERC2 and OCA2, there are actually a lot of other genes that contribute to skin tone.
In case you didn't know. KITLG, TYRP1, ASIP, IRF4 are also big contributors to skin tone.

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Originally Posted by AndreiDNA

go through these GWAS studies.
and type in "HERC2" into "Mapped Gene"
https://www.ebi.ac.uk/gwas/efotraits/OBA_VT0002095

They very much do impact skin color. One of the biggest contributors to it in fact.
Attachment 148674

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So, what you're saying is any European without blue eyes (ie not homozygous for HERC2 blue eyed SNPs) has "Olive Skin"

Just from observation of people that can't be correct

Maybe heterzygous SNPs for HERC2 have a v slight darkening affect on skin tone...

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Originally Posted by Mopi of the Julii

So, what you're saying is any European without blue eyes (ie not homozygous for HERC2 blue eyed SNPs) has "Olive Skin"

Just from observation of people that can't be correct

Maybe heterzygous SNPs for HERC2 have a v slight darkening affect on skin tone...

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no. It is possible to score white, and even palest skin tone with my tool while having hetero HERC2. My tool's skin color prediction takes SLC24A5, SLC45A2, SLC24A4, HERC2, OCA2, ASIP, TYRP1, IRF4, and even MC1R into account. There's many combinations that can yield pale skin with darker eyes.

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Originally Posted by AndreiDNA

The reason Vessna scores olive for skin color is because of her HERC2 genotype. If she was homozygous there, instead of heterozygous, she'd score white skin.
HERC2 is strongly tied to skin color by GWAS. It's one of the most reliable ways of predicting skin shade in europeans, who pretty much unanimously have derived SLC24A5 and SLC45A2. But try explaining that to her... Her goal is badmouthing my tool, that's the reason she purchased the reports in the first place. She and her buddies here dont GAF about the genetics of skin color.

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HERC2 affects primarily eye color, skin pigmentation is influenced by multiple genes. If HERC2 was solely responsible most brown eyed Europeans would have darker skin which obviously isn’t true. There are people like my husband who are homozygous for HERC2 but their skin is darker and tans well.

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Originally Posted by Vessna

HERC2 affects primarily eye color, skin pigmentation is influenced by multiple genes. If HERC2 was solely responsible most brown eyed Europeans would have darker skin which obviously isn’t true. There are people like my husband who are homozygous for HERC2 but their skin is darker and tans well.

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yeah right. read my other replies. HERC2 isn't the single biggest factor in my trait predictor's skin color panel. It's just one of the genes that contribute. There are plenty of cases where folks score palest or white skin tone with my tool with darker eyes

Attachment 148675
some examples of globular amphorans that score palest or white skin tone while being heterozygous for HERC2 (hazel eye prediction)

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Originally Posted by AndreiDNA

yeah right. read my other replies. HERC2 isn't the single biggest factor in my trait predictor's skin color panel. It's just one of the genes that contribute. There are plenty of cases where folks score palest or white skin tone with my tool with darker eyes

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You stated the reason I scored olive skin with your tool was because I am heterozygous for HERC2