I'm not sure, but it quite obviously did.
Proto Slavs make the impression of having a partly immunity. The return of plague at abt. 1350 and the affected areas (green depicts unaffected areas) suggests to me that it's genetical as now the partly Slavic derived Eastern Germans are hardly hit. It may be by chance but to me it seems strinking that now areas that were populated with people that had much of the proto Slavic genetics were spared.
Speculation: Slavs may have been more exposed to this disease that is considered coming from East Asia compared to Germanics that lived more in the west. East Germanics may have been something like new immigrants in eastern Germania magna and been "too east" compared to their origin and thus particularly badly protected.
https://i.imgur.com/z6yjNXM.jpeg

