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Thread: Latest Latin American admixture study from 5 countries published from PLOS genetics

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    Default Latest Latin American admixture study from 5 countries published from PLOS genetics

    Admixture in Latin America: Geographic Structure, Phenotypic Diversity and Self-Perception of Ancestry Based on 7,342 Individuals

    Abstract

    The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, México and Perú). These individuals were also characterized for a range of physical appearance traits and for self-perception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry







    The Brazilian sample (Figure 1A) shows widespread European ancestry with the highest levels being observed in the south. African ancestry is also widespread (except for the south) and reaches its highest values in the East of the country. Native American ancestry is highest in the north-west (Amazonia). The Chilean sample (Figure 1B) shows the least regional variation, with low levels of African ancestry throughout the country. European and Native American ancestry are relatively uniform, although somewhat higher European ancestry is seen around the main urban areas of the north and centre, Native ancestry predominating elsewhere, particularly in the south. The Colombian sample (Figure 1C) shows highest African ancestry in the coastal regions (particularly on the Pacific) and highest European ancestry in central areas. Native ancestry appears highest in the south-west and in the east of the country (Amazonia) but interpolations in these areas are based on few data points. In the Mexican sample (Figure 1D) Native American ancestry is highest in the centre/south of the country with the north showing the highest proportion of European Ancestry. African ancestry is generally low across Mexico except for a few coastal regions. The Peruvian sample (Figure 1E) shows substantial Native American ancestry throughout the country, particularly in the south, European ancestry appears highest around northern/central areas. African ancestry in Peru is generally low, except for parts of the northern coast.
    Recruitment took place mainly in five locations: México City (México), Medellín (Colombia), Lima (Perú), Arica (Chile) and Porto Alegre (Brazil). With the exception of Chile, most subjects recruited in these cities were students and staff from the universities participating in this research.
    it was published a few days ago from plos genetics research center, what are your thoughts on this? to me this was kinda what I expected it to be.
    The link for the full study is down below

    http://www.plosgenetics.org/article/...l.pgen.1004572

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