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Thread: Middle Eastern Red Hair: What mutations produce it?

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    Lightbulb Middle Eastern Red Hair: What mutations produce it?


    In the last week I've read Academic studies online that discovered just a handful of mutations in the MC1R gene can explain over 90% of Red hair in Europe.

    There's prove that Red hair exists in the Middle East, but as far as I know no one has ever tested whether Red hair outside of Europe is caused by the same mutations. If it is, it means Middle Eastern and European Red hair trace back to common ancestor.


    So, what I'm asking is for non-Europeans to post their calls in "Red Hair" SNPs to see if they're carriers. And also if they know of Natural Red hair in their family or countries of origin. Here's a list of "Red Hair" SNPs. You can get results much faster for most of the "Red Hair" SNPs withthis(Just plug in your unzipped DNA file, and click on Hair Color, then genotype). An even faster way, if you tested with 23andme, is to search your Raw Data and get your calls for all MC1R SNPs tested.

    Around 20-60% of North Europeans(Varies by ethnic group) are carriers of Red Hair, even though 1-10% have Red hair. So, even if though Red hair is very rare outside of Europe, carriers are probably not very rare.

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    Red hair markers have been found in various Pre-Historic Europeans(Pre-Historic Carriers of Red Hair). Several are from 1,000s of years before the European gene pool formed, and from people who contributed ancestry to Europeans and Middle Easterns.

    In my opinion Red hair first came about in Upper Paleolithic Eurasia in ANE/WHG related people. Kostenki 14 who lived 36,000 years ago having Red hair variant R151C and being closely related to later ANE/WHG is consistent with this idea. And the people it first arose in contributed ancestry to all West Eurasians. If you look at people living today, Red Hair looks like one of many depigmentation traits that appear to be Euro-specific.

    But the Light skin in Redheads is caused by differnt mutations than the light skin in non-Redheads. Red hair existed in mostly Dark-skinned populations for over 4,000 years at least(Confirmed in Mesolithic Motala), maybe 30,000 years, before Europeans became uniformly Light skinned.

    So, Red hair in the Middle East doesn't have to be explained by European-admixture. That's probably the conclusion some people would come to at first. Instead it is probably from a very distant common ancestor of Europeans and Middle Easterns. It's just random Red hair became more popular in Europe. By popular I mean 3% on average.

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    Several Red hair Variants are found in Middle Eastern and South-Central Asians from HGDP, but not in Africa and East Asia.

    rs1805007




    rs1805008




    rs1805009



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    The highest frequency of R151C(T rs1805007) is in Samartians.

    http://alfred.med.yale.edu/alfred/Si...euid=SI663691F

    The T allele has a frequency of 20.5% out of 78 samples. Most certainly have CT. The association between R151C and Red hair in Europeans has been proven, so there must be some Red hair among the Samartians. They're some of the most ENF of West Asians, with no signs of recent European admixture.

    Red hair has been found in Samartians, but I don't know how common it is. Here are some examples I easily found in Google images.




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    Quote Originally Posted by Fire Haired View Post
    Several Red hair Variants are found in Middle Eastern and South-Central Asians from HGDP, but not in Africa and East Asia.

    rs1805007




    rs1805008




    rs1805009


    Do you know the carrier for Europeans? I had CC, CC and GG for the above.

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    "Several Red hair Variants are found in Middle Eastern and South-Central Asians from HGDP, but not in Africa and East Asia."

    It must be a Caucasoid thing, then.

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    Quote Originally Posted by Grünmann View Post
    "Several Red hair Variants are found in Middle Eastern and South-Central Asians from HGDP, but not in Africa and East Asia."

    It must be a Caucasoid thing, then.
    In ALFRED search a few Han had it. Could be the same mutation popping up twice, with R151C in Han having nothing to do with Red hair, or minor West Eurasian ancestry in Han. Chances of a Han popping up with two derived alleles in rs1805007(Red hair version) is like 0.00001%.

    This Chinese girl is said to have been born with Red hair(according to this article).
    Last edited by Fire Haired; 07-07-2015 at 07:20 AM.

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