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Thread: Neanderthal genes shape modern european phenotypes after all

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    Default Neanderthal genes shape modern european phenotypes after all

    Here, using MRI in a large cohort of healthy individuals of European-descent, we show that the amount
    of Neanderthal-originating polymorphism carried in living humans is related to cranial and brain
    morphology. First, as a validation of our approach, we demonstrate that a greater load of Neanderthal-
    derived genetic variants (higher “NeanderScore”) is associated with skull shapes resembling those of
    known Neanderthal cranial remains, particularly in occipital and parietal bones.
    Next, we demonstrate
    convergent NeanderScore-related findings in the brain (measured by gray- and white-matter volume,
    sulcal depth, and gyrification index) that localize to the visual cortex and intraparietal sulcus. This work
    provides insights into ancestral human neurobiology and suggests that Neanderthal-derived genetic
    variation is neurologically functional in the contemporary population.
    This finding provides crucial validation of the NeanderScore measurement and suggests that even
    in the context of the modern H. sapiens genome, Neanderthal genetic variation is associated with patterns of skull
    dimensions that mirror known Neanderthal phenotypes.
    https://www.nature.com/articles/s41598-017-06587-0.pdf

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    It has also been argued that red hair was derived from Neanderthals. However those possessed a different sequence on the gene responsible for the mutation. Anyway this is a very interesting since it hints that Neanderthals' contribution has been crucial for the evolution of the European stock. Should be more extensively discussed. Anyone who knows perhaps more? Please contribute!

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    this makes perfect sense because homo sapiens tend to look negroid. Europeans are composed of CM and neanderthals

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    Quote Originally Posted by Frequency115 View Post
    this makes perfect sense because homo sapiens tend to look negroid. Europeans are composed of CM and neanderthals
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    East Asians have more Neanderthal admixture than Europeans. So?

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    Quote Originally Posted by LoLeL View Post
    East Asians have more Neanderthal admixture than Europeans. So?
    Yes but Asians evolved differently than Europeans did. Neanderthal werent mongoloids based on the skulls we have found in Europe

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