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A 2017 study on genetic affinities among the historical provinces of Romania and Central Europe as revealed by an mtDNA analysis
Full Study: https://bmcgenet.biomedcentral.com/a...863-017-0487-5
Finding
"In our mtDNA analysis, we observed a uniform distribution of the majority of haplogroups among Romanian provinces with the populations in the Wallachia, Moldavia, and Dobrudja provinces tended to cluster together within the Slav population based on the MDS scatterplots, while Transylvania was more closely related to Central European populations. We confirmed gene flow from Southwestern Asia based on pairwise population F ST values strictly in the case of Dobrudja, and this result could be easily explained by the greater Asian influence in this area throughout history.
Our findings suggesting a closer affinity of Transylvania to central Europe are supported by the observed haplogroup frequency clines for several European and Asian maternal lineages and could be attributed to different migratory routes shaped by the Carpathian Arch.
The mitochondrial DNA data in this study and the analysis of differentiation among historical regions represent a considerable extension of our knowledge of mitochondrial diversity in Romania."
Below is a multi-dimensional scaling plot of pairwise FST-values of the Romanian populations and other 19 neighboring populations. The FST genetic distances were calculated based on the mtDNA haplogroup frequencies of different populations: Romanian provinces (in red) and neighboring populations (blank circles)
Below is a map of Romania showing the approximate migration routes and the mtDNA haplogroup distribution in the Romanian provinces. The map depicts the geographic distribution of mtDNA haplogroups in the Romanian provinces as reported in Additional file 2: Table S3: Wallachia (yellow), Dobrudja (blue), Moldavia (green) and Transylvania (red). Arrows indicate the approximate migration routes running east to west direction that seemed to be used throughout the history since Neolithic period to Middle Ages. The map was constructed by M.C. and R.C
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