Neanderthal Gene Protects against covid

[MechtoidAfalouHG]

Reposting from different forum

https://www.nature.com/articles/s41591-021-01281-1

A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity

Sirui Zhou, Guillaume Butler-Laporte, […]J. Brent Richards
Nature Medicine (2021)Cite this article

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Abstract
To identify circulating proteins influencing Coronavirus Disease 2019 (COVID-19) susceptibility and severity, we undertook a two-sample Mendelian randomization (MR) study, rapidly scanning hundreds of circulating proteins while reducing bias due to reverse causation and confounding. In up to 14,134 cases and 1.2 million controls, we found that an s.d. increase in OAS1 levels was associated with reduced COVID-19 death or ventilation (odds ratio (OR) = 0.54, P = 7 × 10−8), hospitalization (OR = 0.61, P = 8 × 10−8) and susceptibility (OR = 0.78, P = 8 × 10−6). Measuring OAS1 levels in 504 individuals, we found that higher plasma OAS1 levels in a non-infectious state were associated with reduced COVID-19 susceptibility and severity. Further analyses suggested that a Neanderthal isoform of OAS1 in individuals of European ancestry affords this protection. Thus, evidence from MR and a case–control study support a protective role for OAS1 in COVID-19 adverse outcomes. Available pharmacological agents that increase OAS1 levels could be prioritized for drug development.


And the good news is both 23andMe(V3) and FT-DNA measured rs10774671

"It is therefore necessary to have an ancestral allele (G) for that "the protective effect size was particularly large, such that a 50% decrease in the odds of very severe COVID-19 was observed"

I am G/A[IMG]

[/IMG]

[de Burgh II]

[Dick]

Covid is white suprematism. Cancel it nao

[MechtoidAfalouHG]

Covid is white suprematism. Cancel it nao

Well its from China so canceling it would be racist towards the Yellows

[Dick]

Well its from China so canceling it would be racist towards the Yellows

Remember when Dr Fraudski said African Americans should get the vaccine first

[de Burgh II]

Covid is white suprematism. Cancel it nao

Covid-19 is natural selection in the process; nature culls people who don't have this immunity/genes and spares people like me and mechtoid19 from the severity of covid-19's virus attack on a person's lungs. That is why most of the Native Americans died out when the European colonialists brought over diseases they weren't used to. Natural selection made most Latinos/Latinas hybridized tri-racials that gives them hybrid vigor.

Hybrid Vigor/Heterosis:

Since the early 1900s, two competing genetic hypotheses, not necessarily mutually exclusive, have been developed to explain hybrid vigor. More recently, an epigenetic component of hybrid vigor has also been established.[11][12]

The genetic dominance hypothesis attributes the superiority of hybrids to the masking of expression of undesirable (deleterious) recessive alleles from one parent by dominant (usually wild-type) alleles from the other (see Complementation (genetics)). It attributes the poor performance of inbred strains to the expression of homozygous deleterious recessive alleles. The genetic overdominance hypothesis states that some combinations of alleles (which can be obtained by crossing two inbred strains) are especially advantageous when paired in a heterozygous individual. This hypothesis is commonly invoked to explain the persistence of some alleles (most famously the Sickle cell trait allele) that are harmful in homozygotes. In normal circumstances, such harmful alleles would be removed from a population through the process of natural selection. Like the dominance hypothesis, it attributes the poor performance of inbred strains to expression of such harmful recessive alleles. In any case, outcross matings provide the benefit of masking deleterious recessive alleles in progeny. This benefit has been proposed to be a major factor in the maintenance of sexual reproduction among eukaryotes, as summarized in the article Evolution of sexual reproduction. [...]

https://en.wikipedia.org/wiki/Heterosis

In layman's terms, by making a person's successive generations more heterogeneous/diverse; one's genetic fitness is enhanced in nature to combat new viruses/ environmental pressures that will force people to adapt to the new environment that they are exposed to.

Each race has their own ecological niche that they were forced to adapt to that determined how they genes were expressed in their current environment. Nevertheless, that is simply how natural selection works when it is controlled under the right circumstances. Modern medicine and the modern welfare state goes against the natural order of natural selection because it takes away nature's ability to weed out maladaptive/"weak" genes such as low-intelligence, mentally-unstable and "criminal" genetics.

Nevertheless, we will have to see nature's plans when it comes in due time....

[Dick]

Covid-19 is natural selection in the process; nature culls people who don't have this immunity/genes and spares people like me and mechtoid19 from the severity of covid-19's virus attack on a person's lungs. That is why most of the Native Americans died out when the European colonialists brought over diseases they weren't used to. Natural selection made most Latinos/Latinas hybridized tri-racials that gives them hybrid vigor.

Hybrid Vigor/Heterosis:



https://en.wikipedia.org/wiki/Heterosis

In layman's terms, by making a person's successive generations more heterogeneous/diverse; one's genetic fitness is enhanced in nature to combat new viruses/ environmental pressures that will force people to adapt to the new environment that they are exposed to.

Each race has their own ecological niche that they were forced to adapt to that determined how they genes were expressed in their current environment. Nevertheless, that is simply how natural selection works when it is controlled under the right circumstances. Modern medicine and the modern welfare state goes against the natural order of natural selection because it takes away nature's ability to weed out maladaptive/"weak" genes such as low-intelligence, mentally-unstable and "criminal" genetics.

Nevertheless, we will have to see nature plans when it comes in due time....

Well now you know where our 23andme results went, to Wuhan.

[de Burgh II]

Well now you know where our 23andme results went, to Wuhan.

Its a fair trade if you ask me; it gives me insight to explore my dna further. Everything in life comes at a cost, you just have to play cards right under the right circumstances.

[Dick]

Its a fair trade if you ask me; it gives me insight to explore my dna further. Everything in life comes at a cost, you just have to play cards right under the right circumstances.

The Jews sold our DNA to the chinks , bro

[de Burgh II]

The Jews sold our DNA to the chinks , bro

The same could be said with Zuckerberg (Jew) with his Asian wife selling your Facebook information to third party companies/sites to the highest bidder...

No matter which way we look at it... in the modern age... we are all equally fucked...