Are people of European origin genetically prone to nicotine dependence?

[Don]

Well, this is an interesting subject, tabú since racial critic differences are involved.

In the matter are involved the enzimes, as lactasa and Deshidrogenasa (spanish).
European population have been exposed to non processed (non fermented mainly) milk in adult stages as well to exposed to alcohol in critic episodes of the vital life (read here previous copulation or previous battle).

Alcohol exposure has been a constant in europeans.

We will understand easily that the less adapted (read here: the individual with less amount of the specific enzyme to "deal" with the alcohol, for example) had less success in the sexual relation after drinking lots of alcohol in the solstice party in a celtiberian tribe (as european example) or would have his motricity enough afected in a violent confrontation that would impede of difficult the survival. (selective breed).

The same happens with the adults with tolerance to the lactose (presence in adult stages of lactase enzyme, only produced in early stages except mutations). They would have extra amount of decisive nutrients.

So, the alcoholism seems to be more common in europeans than in asiatic, for example, because the major presence of deshidrogenasa among the first, would act as a "shield" that will hide the nocive effects of alcohol until reaching critical stages of dependence.

It's quite easy see this example among southamericans, whose tolerance or "mal beber" ("bad drinking" -losing easily control and massive behaviour consequences with low amount of alcohol, related to low presence of deshidrogenasa-) can be easily related to the amerindian phenotype.

[Lulletje Rozewater]

Some claim this is how the American Indians got their revenge on the white man for introducing alcohol to their populations.

I found this interesting article:

http://ajp.psychiatryonline.org/cgi/...165/9/1089.pdf

Anyone know more about this?

Look at these figures in America.
http://www.cancer.org/docroot/PED/co...te_Smoking.asp

[Spiderman]

Europeans are not bad compared to Asians. In my travels, I have seen people [typically of the C YdNa genotype from southern asia] almost chain smoke if they can afford it. It reminded me of references in literature to the pervasiveness of "opium dens" in asian communities around the turn of the previous century.

[ricko0812]

In the United States it also depends on the area because in my home state tobacco is very cheap compared to some parts of the country due to my state being very pro-tobacco. I have worked in tobacco fields before and it is very hard work.

[Hurrem sultana]

pff. Thanks for the cigs, redman. Have a swig of my firewater.

thanks for the lung cancer


yeah..pff

[arcticwolf]

thanks for the lung cancer


yeah..pff

Sis, are you one of the health nuts? What's the point of dying healthy?

[Damião de Góis]

I have this on my 23andme:

AG - In Europeans who smoke, likely to smoke one more cigarette per day on average than the typical amount.

But it's not really true.

[Pallantides]

Me:

Smoking Behavior

AA In Europeans who smoke, likely to smoke two more cigarettes per day on average than the typical amount.


Nicotine Dependence

AA Slightly higher odds of nicotine dependence.

[Mortimer]

im prone to nicotine abuse, even written in my 23andMe health profile "if smoker likely smokes more"....

[Scrapple]

AG In Europeans who smoke, likely to smoke one more cigarette per day on average than the typical amount.

I used to only smoke when I drank before it was banned in bars but never otherwise.