PDA

View Full Version : Do you have Asian or European SNP at these locations



Zoro
08-06-2022, 03:16 PM
I came across this table in “Shifts in the Genetic Landscape of the Western Eurasian Steppe Associated with the Beginning and End of the Scythian Dominance”
https://www.cell.com/cms/10.1016/j.c...468b364b8/mmc1

I was curious whether present day individuals Europeans or others have the “Asian” or “European “ SNP at these locations. My guess is Europeans would be somewhat similar to Srubnaya or western Scythians.

For ex if you have GG at rs12036383 it would be 00 or you would write 0/1. However if you’re GA you have 1 copy of the Asian SNP and you can write 1/1https://i.imgur.com/kZByZAC.jpg

Grace O'Malley
08-06-2022, 03:28 PM
I'm GG so European not surprisingly.

https://i.imgur.com/WhjYcCK.png

Zoro
08-06-2022, 03:53 PM
I'm GG so European not surprisingly.

https://i.imgur.com/WhjYcCK.png

Only 1 SNP ! Bummer. I thought 23andme would at least have a few SNPs from the list.

It’s hard to draw conclusions from just 1 SNP. I’m sure if you had all these SNPs genotyped such as if you gad WGS data 1 or 2 would be Asian. Notice that the samples mostly had “European” SNPs

Mortimer
08-06-2022, 03:57 PM
Bro i will look it up tomorrow when im on my Laptop now im on my phone but sorry off topic question which calculator did you run this thanks
Ancestry
74.31% W. Eurasian + 11.42% E. Eurasian + 5.42% S. Eurasian + 8.85% Basal

Zoro
08-06-2022, 04:07 PM
Bro i will look it up tomorrow when im on my Laptop now im on my phone but sorry off topic question which calculator did you run this thanks
Ancestry
74.31% W. Eurasian + 11.42% E. Eurasian + 5.42% S. Eurasian + 8.85% Basal

I didn’t use calculator i did it with qpadm

Guti
08-06-2022, 04:11 PM
For me rs12036383 is 'not genotyped'.

https://i.postimg.cc/bJvNw1R4/rs12036383.jpg


I will try also other SNPs right now.

Zoro
08-06-2022, 04:14 PM
If anyone is curious how many of the 17 snps on that list you’ll get if you do WGS test for example at Nebula. My Kurdish cousin did it and he got 17of the 18 snps. Thats why it’s good idea to do WGS test you get alot more snps than 23andme test

This is his SNPs. He had 5/17 Asian SNPs I think some E. Europeans of similar longitude as Kurdiistan would get something similar

https://i.imgur.com/63RJpF4.jpg

Mortimer
08-06-2022, 04:15 PM
I didn’t use calculator i did it with qpadm

What is that and could you do this for me too please thanks

Zoro
08-06-2022, 04:26 PM
What is that and could you do this for me too please thanks

Sorry didn’t mean I personally ran it. Dilawer from Eurasiandna ran it for me. You can try to see if he’s still doing it for people. His email is dilawer@eurasiandna.com

Oturan Boğa
08-06-2022, 04:28 PM
From FTDNA's raw data

rs12036383 GG
rs78404020 AA
rs3827760 AA
rs2148360 TT
rs1426654 AA
rs11657785 TT

Guti
08-06-2022, 04:32 PM
I have only 3 SNPs genotyped. 1 match with the Cimmerians.

rs16891982
https://i.postimg.cc/g0BS56gG/82.jpg


rs1426654
https://i.postimg.cc/hj1JvVNB/rs1426654.jpg

rs3827760
https://i.postimg.cc/6p8Gc24r/rs3827760.jpg

Zoro
08-06-2022, 04:50 PM
I have only 3 SNPs genotyped. 2 matches with the Cimmerians.

rs16891982
https://i.postimg.cc/g0BS56gG/82.jpg

rs1426654
https://i.postimg.cc/hj1JvVNB/rs1426654.jpg



rs3827760
https://i.postimg.cc/6p8Gc24r/rs3827760.jpg

Looks like you had 1 Asian and 2 European so 1/3 but that percentage will change if you had 17snps genoytped. Yes Srubnaya Cimmerians and Scythian Kazakhstan also had Asian gene at your location

Guti
08-06-2022, 05:00 PM
Looks like you had 1 Asian and 2 European so 1/3 but that percentage will change if you had 17snps genoytped. Yes Srubnaya Cimmerians and Scythian Kazakhstan also had Asian gene at your locationfor rs1426654 I have AA. In this case it is G that is ASN (East Asian modal allele).

Same can be said about rs3827760. It is also AA. Nothing ASN (East Asian modal allele) about it.

Rædwald
08-06-2022, 05:27 PM
rs61766198 N/A not genotyped

rs12036383 G/G EUR

rs78404020 A/A EUR

rs3827760 A/G EUR/ASN

rs922452 N/A not genotyped

rs1250221 N/A not genotyped

rs4365635 N/A not genotyped

rs16891982 G/G EUR

rs6927195 N/A not genotyped

rs71551254 N/A not genotyped

rs11778591 N/A not genotyped

rs2148360 N/A not genotyped

rs10826399 N/A not genotyped

rs12434466 A/A ANC/EUR

rs1426654 A/A EUR

rs61691136 N/A not genotyped

rs11657785 N/A not genotyped

rs6053171 N/A not genotyped

Zoro
08-06-2022, 06:06 PM
for rs1426654 I have AA. In this case it is G that is ASN (East Asian modal allele).

Same can be said about rs3827760. It is also AA. Nothing ASN (East Asian modal allele) about it.

I know but you have 1 E Asian allele at rs16891982. Your genotype is CG. My Kurdish cousin was CC so he had 2 Asian alleles at that location If you look at the table C is Asian allele. I am sure he would have more asian Alleles just like my cousin (maybe 1 or2 less Asian since your Yezidi. if you had the other SNPs. Maybe you should do WGS test so you can see the rest of your snps

Guti
08-06-2022, 06:32 PM
I know but you have 1 E Asian allele at rs16891982. Your genotype is CG. My Kurdish cousin was CC so he had 2 Asian alleles at that location If you look at the table C is Asian allele. I am sure he would have more asian Alleles just like my cousin (maybe 1 or2 less Asian since your Yezidi. if you had the other SNPs. Maybe you should do WGS test so you can see the rest of your snpsOk, but that is just 1 out of 6 alleles known to me. That is only 1/6 East Asian modal allele.

It is possible that there are some ancient East Asian modal alleles in Kurds. But most of those alleles are probably from very ancient sources (at least 2000 years old) and not from more recent Turkic/Turcoman sources. In my case it is probably from the ancient Eastern Iranic people. It has nothing to do with the Turks.

Zoro
08-06-2022, 06:39 PM
If anyone is curious how many of the 17 snps on that list you’ll get if you do WGS test for example at Nebula. My Kurdish cousin did it and he got 17of the 18 snps. Thats why it’s good idea to do WGS test you get alot more snps than 23andme test

This is his SNPs. He had 5/17 Asian SNPs I think some E. Europeans of similar longitude as Kurdiistan would get something similar

https://i.imgur.com/63RJpF4.jpg

I just checked the map and Tatarstan is about the same longitude as Kurdistan (Zagros). Since Tataristan is as far east as Kurdistan I expect people from that area of Russia who are not heavily E. Asian admixed to have as many E. Asian alleles as Kurds. So basically 5 or more locations with E. Asian alleles.

Anyone from that part of Russia so we can check?

Zoro
08-06-2022, 06:46 PM
Ok, but that is just 1 out of 6 alleles known to me. That is only 1/6 East Asian modal allele.

It is possible that there are some ancient East Asian modal alleles in Kurds. But most of those alleles are probably from very ancient sources (at least 2000 years old) and not from more recent Turkic/Turcoman sources. In my case it is probably from the ancient Eastern Iranic people. It has nothing to do with the Turks.

Whenever you decide to do WGS we can see what your other snps show

kingmob
08-06-2022, 06:53 PM
rs12036383 GG
rs78404020 AA
rs3827760 AA
rs922452 CC
rs1250221 CC
rs4365635 CT
rs16891982 GG
rs6927195 CC
rs11778591 AC
rs2148360 TT
rs10826399 GT
rs12434466 AG
rs1426654 AA
rs61691136 TT
rs11657785 TT
rs6053171 GG



Help decipher, plx.

Zoro
08-06-2022, 07:34 PM
rs12036383 GG
rs78404020 AA
rs3827760 AA
rs922452 CC
rs1250221 CC
rs4365635 CT
rs16891982 GG
rs6927195 CC
rs11778591 AC
rs2148360 TT
rs10826399 GT
rs12434466 AG
rs1426654 AA
rs61691136 TT
rs11657785 TT
rs6053171 GG



Help decipher, plx.

Total 4 Asian alleles. How did you get so many SNPs. Do you have WGS or are they imputed ?

https://i.imgur.com/kZByZAC.jpg

kingmob
08-06-2022, 08:41 PM
WGS.

gixajo
08-06-2022, 09:25 PM
If anyone is curious how many of the 17 snps on that list you’ll get if you do WGS test for example at Nebula. My Kurdish cousin did it and he got 17of the 18 snps. Thats why it’s good idea to do WGS test you get alot more snps than 23andme test

This is his SNPs. He had 5/17 Asian SNPs I think some E. Europeans of similar longitude as Kurdiistan would get something similar

]

If you give us the list of SNPs directly written without taking a screenshot, to copy and paste them directly, it will be easier and faster for us to search for them all.

Edit:nevermind, I did it myself:

rs12036383
rs78404020
rs3837760
rs922452
rs1250221
rs4365635
rs16891982
rs6927195
rs71551254
rs11778591
rs2148360
rs10826399
rs12434466
rs1426654
rs61691136
rs11657785
rs6053171

gixajo
08-06-2022, 09:34 PM
About rs12036383 this is what I get:

https://i.postimg.cc/yYq4hL6d/GG-rs.png (https://postimages.org/)

chinshen
08-06-2022, 09:41 PM
If you ask Guti then I only have Semitic African DNA, no Asian or European :cool:.
Nevertheless here are mine:

rs16891982 5 33951693 CC
rs1426654 15 48426484 AA
rs3827760 2 109513601 AA

Zoro
08-06-2022, 10:06 PM
If you give us the list of SNPs directly written without taking a screenshot, to copy and paste them directly, it will be easier and faster for us to search for them all.

I’m sure these aren’t the only snps with large differentiation frequency between Asians and Europeans. There’s got to be thousands

rs61766198
rs12036383
rs78404020
rs3827760
rs922452
rs1250221
rs4365635
rs16891982
rs6927195
rs71551254
rs11778591
rs2148360
rs10826399
rs12434466
rs1426654
rs61691136
rs11657785
rs6053171

Zoro
08-06-2022, 10:08 PM
If you ask Guti then I only have Semitic African DNA, no Asian or European :cool:.
Nevertheless here are mine:

rs16891982 5 33951693 CC
rs1426654 15 48426484 AA
rs3827760 2 109513601 AA

Funny. There’s no corner of west Asia that doesn’t have some recent or ancient Asian or European admixture

chinshen
08-06-2022, 10:19 PM
Funny. There’s no corner of west Asia that doesn’t have some recent or ancient Asian or European admixture

Everyone has a bit of everyone else's dna, after all West Asia is still part of Asia. Except for Guti of course, he is pure Aryan only.

gixajo
08-06-2022, 10:22 PM
I’m sure these aren’t the only snps with large differentiation frequency between Asians and Europeans. There’s got to be thousands



I already did it myself, don´t worry.

Here is what I get in my 23andMe raw data:


rs12036383 GG
rs78404020 AA
rs3837760 -no genes or markers found matching-
rs922452 -no genes or markers found matching-
rs1250221 -no genes or markers found matching-
rs4365635 -no genes or markers found matching-
rs16891982 GG
rs6927195 -found but not genotyped-
rs71551254 -no genes or markers found matching-
rs11778591 -no genes or markers found matching-
rs2148360 -no genes or markers found matching-
rs10826399 -no genes or markers found matching-
rs12434466 AA
rs1426654 AA
rs61691136 -no genes or markers found matching-
rs11657785 -no genes or markers found matching-
rs6053171 -no genes or markers found matching-

gixajo
08-06-2022, 10:29 PM
You didn´t post this before or I didn´t copy it:


rs61766198 -no genes or markers found matching-

Guti
08-06-2022, 10:31 PM
Funny. There's no corner of west Asia that doesn’t have some recent or ancient Asian or European admixtureThose so called 'European' alleles in me (AA) are not really 'European'. They are most likely 'Western Eurasian', be it derived from the Anatolian farmers or Iran_Chl/CHG people.

I know what your purpose was, making Eastern Eurasian/Mongoloid alleles more acceptable to Western Eurasian populations, like we are all the same. But I think you failed in your purpose.
There is still a clear division between Western Eurasians (Europeans/Europoids, Semitics, Caucasians/Iranics) and Eastern Eurasians (Mongoloids, Turks/Tatars).

Zoro
08-06-2022, 11:25 PM
Those so called 'European' alleles in me (AA) are not really 'European'. They are most likely 'Western Eurasian', be it derived from the Anatolian farmers or Iran_Chl/CHG people.

I know what your purpose was, making Eastern Eurasian/Mongoloid alleles more acceptable to Western Eurasian populations, like we are all the same. But I think you failed in your purpose.
There is still a clear division between Western Eurasians (Europeans/Europoids, Semitics, Caucasians/Iranics) and Eastern Eurasians (Mongoloids, Turks/Tatars).

Why do you always twist things around. That table isn’t mine it’s is from a paper. I was just trying to see how modern people compare to the ancient ones they have but it doesn’t seem that people here have enough snps to make a good comparison.Is there a problem with that ??

It seems that you’re pissed because you have an E Asian allele from the few you posted. No need to get upset I’m sure you’ll find that you have alot more E Asian alleles if you do a WGS test. Wouldn’t it be funny if you end up with same number of Asian alleles as Turks.Get over it.

Mortimer
08-06-2022, 11:53 PM
If you give us the list of SNPs directly written without taking a screenshot, to copy and paste them directly, it will be easier and faster for us to search for them all.

Edit:nevermind, I did it myself:

rs12036383
rs78404020
rs3837760
rs922452
rs1250221
rs4365635
rs16891982
rs6927195
rs71551254
rs11778591
rs2148360
rs10826399
rs12434466
rs1426654
rs61691136
rs11657785
rs6053171

For the rest of the SNPS I have no results

SLC45A2 rs16891982
Build 37 33951693 C or G G / G
Build 38 33951588 C or G G / G

SLC24A5 rs1426654
Build 37 48426484 A or G A / G
Build 38 48134287 A or G A / G

SLC24A5 rs1426654
Build 37 48426484 A or G A / G
Build 38 48134287 A or G A / G

Defcon2
08-07-2022, 09:37 AM
Why do you always twist things around. That table isn’t mine it’s is from a paper. I was just trying to see how modern people compare to the ancient ones they have but it doesn’t seem that people here have enough snps to make a good comparison.Is there a problem with that ??

It seems that you’re pissed because you have an E Asian allele from the few you posted. No need to get upset I’m sure you’ll find that you have alot more E Asian alleles if you do a WGS test. Wouldn’t it be funny if you end up with same number of Asian alleles as Turks.Get over it.

How to search the raw data snps of Nebula? I don't have an active subscription.

Zoro
08-07-2022, 01:44 PM
How to search the raw data snps of Nebula? I don't have an active subscription.

I just checked. It looks you can download your vcf file and bam and fasta file. I would just download the vcf file and extract this positions in this table. You’ll need to install vcftools on a linux machine and run this command:

vcftools —gzvcf your_data.vcf.gz —positions a.txt —recode —out your_output

a.txt is a text file you make with 2 columns where column 1 is chromosome number and column 2 is position number you want to extract from your data.

If for some reason you want someone to re-check the genotyping Nebula did it’s a very complicated and time consuming process and there’s only one expert i’m familiar with that can genotype you from your fasta file. It’s Dilawer with Eurasian DNA. Same thing if you want someone to re-genotype you using Hg37 instead of Hg38 human reference

Voskos
08-07-2022, 01:49 PM
I only had one allele of those in the ftdna I took back in 2015 or something. It was euro

Voskos
08-07-2022, 02:13 PM
Wouldn’t it be funny if you end up with same number of Asian alleles as Turks.Get over it.

There's Indians and Bangla with more East Asian than Turks, doesn't mean anything really. Different sources of East Asian, different macronations.

Other than that, nice thread.

Roy
08-10-2022, 08:11 PM
I'm GG so European not surprisingly.

https://i.imgur.com/WhjYcCK.png

I am G/G on this variant too.

someonenotyou
08-14-2022, 03:38 PM
SLC35F3 rs12036383
Build 37 234342067 A or G G / G
Build 38 234206321 A or G G / G

intergenic rs78404020
Build 37 26113913 A or G A / A
Build 38 25891044 A or G A / A

SLC45A2 rs16891982
Build 37 33951693 C or G C / G
Build 38 33951588 C or G C / G

MYLK4 rs6927195
Build 37 2745352 C or G not genotyped
Build 38 2745118 C or G not genotyped

VRK1 rs12434466
Build 37 97324289 A or G A / A
Build 38 96857952 A or G A / A

SLC24A5 rs1426654
Build 37 48426484 A or G A / A
Build 38 48134287 A or G A / A

Gallop
08-14-2022, 05:01 PM
Father

rs61766198
rs12036383 G/G
rs78404020 A/A
rs3827760 A/A
rs922452
rs1250221
rs4365635
rs16891982
rs6927195
rs71551254
rs11778591
rs2148360 T/T
rs10826399
rs12434466
rs1426654 A/A
rs61691136
rs11657785 T/T
rs6053171


Mine

rs61766198
rs12036383
rs78404020
rs3827760 A/A
rs922452
rs1250221
rs4365635
rs16891982
rs6927195
rs71551254
rs11778591
rs2148360
rs10826399
rs12434466
rs1426654 A/A
rs61691136
rs11657785
rs6053171